Colorectal Cancer Research Today is a free monthly online journal that collates and summarizes the latest research about Colorectal Cancer, including details on symptoms, genetics, screening, treatment, information.

Volume 5 (2008), Issue 6 (June)

1. Human methanogen diversity and incidence in healthy and diseased colonic groups using mcrA gene analysis.
   BMC Microbiol, 8: 79. [Abstract] [Full-text]
2. Insig2 is associated with colon tumorigenesis and inhibits Bax-mediated apoptosis.
   Int J Cancer, 123(2): 273-82. [Abstract] [Full-text]
3. Potentiation of chemotherapeutic drugs by energy metabolism inhibitors 2-deoxyglucose and etomoxir.
   Int J Cancer, 123(2): 476-83. [Abstract] [Full-text]
4. REG1A expression is a prognostic marker in colorectal cancer and associated with peritoneal carcinomatosis.
   Int J Cancer, 123(2): 409-13. [Abstract] [Full-text]
5. The risk of extra-colonic, extra-endometrial cancer in the Lynch syndrome.
   Int J Cancer, 123(2): 444-9. [Abstract] [Full-text]
6. Carcinoembryonic antigen and CD44 variant isoforms cooperate to mediate colon carcinoma cell adhesion to E- and L-selectin in shear flow.
   J Biol Chem, 283(23): 15647-55. [Abstract] [Full-text]
7. Assessment of intrafractional movement and internal motion in radiotherapy of rectal cancer using megavoltage computed tomography.
   Int J Radiat Oncol Biol Phys, 71(3): 934-9. [Abstract] [Full-text]
8. Phase I-II trial of concurrent capecitabine and oxaliplatin with preoperative intensity-modulated radiotherapy in patients with locally advanced rectal cancer.
   Int J Radiat Oncol Biol Phys, 71(3): 748-55. [Abstract] [Full-text]
9. Effect of postoperative morbidity on long-term survival after hepatic resection for metastatic colorectal cancer.
   Ann Surg, 247(6): 994-1002. [Abstract] [Full-text]
10. Massive lower gastrointestinal hemorrhage caused by a large extraluminal leiomyoma of the colon: report of a case.
    Dis Colon Rectum, 51(6): 975-8. [Abstract] [Full-text]
11. Risk factors and oncologic impact of anastomotic leakage after rectal cancer surgery.
    Dis Colon Rectum, 51(6): 902-8. [Abstract] [Full-text]
12. High-resolution anoscopy targeted surgical destruction of anal high-grade squamous intraepithelial lesions: a ten-year experience.
    Dis Colon Rectum, 51(6): 829-35; discussion 835-7. [Abstract] [Full-text]
13. Preoperative T staging of colorectal cancer by CT colonography.
    Dis Colon Rectum, 51(6): 875-81. [Abstract] [Full-text]
14. PET/CT colonography for the preoperative evaluation of the colon proximal to the obstructive colorectal cancer.
    Dis Colon Rectum, 51(6): 882-90. [Abstract] [Full-text]
15. Laparoscopic resection of rectal cancer: a comparison of surgical and oncologic outcomes between extraperitoneal and intraperitoneal disease locations.
    Dis Colon Rectum, 51(6): 844-51. [Abstract] [Full-text]
16. A desmoid tumor-staging system separates patients with intra-abdominal, familial adenomatous polyposis-associated desmoid disease by behavior and prognosis.
    Dis Colon Rectum, 51(6): 897-901. [Abstract] [Full-text]
17. Benefits of povidone-iodine solution in colorectal operations: science or legend.
    Dis Colon Rectum, 51(6): 966-71. [Abstract] [Full-text]
18. Colorectal adenomas in young patients: microsatellite instability is not a useful marker to detect new cases of Lynch syndrome.
    Dis Colon Rectum, 51(6): 909-15. [Abstract] [Full-text]
19. Controlling a presacral hemorrhage by using a saline bag: report of a case.
    Dis Colon Rectum, 51(6): 972-4. [Abstract] [Full-text]
20. Sentinel node mapping does not improve staging of lymph node metastasis in colonic cancer.
    Dis Colon Rectum, 51(6): 891-6. [Abstract] [Full-text]
21. Expression and enzyme activity of alpha(1,6)fucosyltransferase in human colorectal cancer.
    Int J Cancer, 123(3): 641-6. [Abstract] [Full-text]
22. Uncertain pathogenicity of MSH2 variants N127S and G322D challenges their classification.
    Int J Cancer, 123(3): 720-4. [Abstract] [Full-text]
23. Growth inhibition of colon cancer cells by polyisoprenylated benzophenones is associated with induction of the endoplasmic reticulum response.
    Int J Cancer, 123(3): 687-94. [Abstract] [Full-text]
24. Dairy products, polymorphisms in the vitamin D receptor gene and colorectal adenoma recurrence.
    Int J Cancer, 123(3): 586-93. [Abstract] [Full-text]
25. Association of family history with cancer recurrence and survival among patients with stage III colon cancer.
    JAMA, 299(21): 2515-23. [Abstract] [Full-text]
26. Colorectal cancer in the elderly. Is there a role for safe and curative surgery?
    ANZ J Surg, 78(6): 466-70. [Abstract] [Full-text]
27. Pelvic drainage for anterior resection revisited: use of drains in anastomotic leaks.
    ANZ J Surg, 78(6): 461-5. [Abstract] [Full-text]
28. Clinicians' attitudes towards management of metastatic colorectal adenocarcinoma.
    ANZ J Surg, 78(6): 454-60. [Abstract] [Full-text]
29. Antitumor actions of a chromone glucoside cnidimoside A isolated from Cnidium japonicum.
    Nat Med (Tokyo), 62(3): 308-13. [Abstract] [Full-text]
30. Preoperative capecitabine and accelerated intensity-modulated radiotherapy in locally advanced rectal cancer: a phase II trial.
    Am J Clin Oncol, 31(3): 264-70. [Abstract] [Full-text]
31. ERK signaling in colorectal cancer: a preliminary report on the expression of phosphorylated ERK and the effects of radiation therapy.
    Am J Clin Oncol, 31(3): 255-8. [Abstract] [Full-text]
32. Relationship between risk information on total colonoscopy and patient preferences for colorectal cancer screening options: analysis using the analytic hierarchy process.
    BMC Health Serv Res, 8: 106. [Abstract] [Full-text]
33. Aberrant promoter methylation and tumor suppressive activity of the DFNA5 gene in colorectal carcinoma.
    Oncogene, 27(25): 3624-34. [Abstract] [Full-text]
34. Nuclear GSK-3beta inhibits the canonical Wnt signalling pathway in a beta-catenin phosphorylation-independent manner.
    Oncogene, 27(25): 3546-55. [Abstract] [Full-text]
35. Clinicopathological analysis of colorectal cancers with PIK3CA mutations in Middle Eastern population.
    Oncogene, 27(25): 3539-45. [Abstract] [Full-text]
36. Endpoints and surrogate endpoints in colorectal cancer: a review of recent developments.
    Curr Opin Oncol, 20(4): 466-71. [Abstract] [Full-text]
37. First-line chemotherapy in metastatic colorectal cancer: new approaches and therapeutic algorithms. Always hit hard first?
    Curr Opin Oncol, 20(4): 459-65. [Abstract] [Full-text]
38. Implementation of the scientific evidence into daily practice--example from fast-track colonic cancer surgery.
    Colorectal Dis, 10(6): 593-8. [Abstract] [Full-text]
39. Colo-anal pouches: lessons from a prospective audit.
    Colorectal Dis, 10(6): 599-604. [Abstract] [Full-text]
40. Pathologic response assessed by Mandard grade is a better prognostic factor than down staging for disease-free survival after preoperative radiochemotherapy for advanced rectal cancer.
    Colorectal Dis, 10(6): 563-8. [Abstract] [Full-text]
41. Straight to test. Results of a pilot study in a hospital serving an inner city population.
    Colorectal Dis, 10(6): 569-76. [Abstract] [Full-text]
42. Adenocarcinoma of the anal transitional zone after double stapled ileal pouch-anal anastomosis for ulcerative colitis.
    Colorectal Dis, 10(6): 621-3. [Abstract] [Full-text]
43. Anorectal amelanotic melanoma.
    Colorectal Dis, 10(6): 612-5. [Abstract] [Full-text]
44. High efficiency reconstitution of a human-mouse chimeric Fab of CAb-1 antibody specific to human colon cancer.
    Scand J Immunol, 68(1): 12-21. [Abstract] [Full-text]
45. Human colon cancer stem cells: a new paradigm in gastrointestinal oncology.
    J Clin Oncol, 26(17): 2828-38. [Abstract] [Full-text]
46. DACT3 is an epigenetic regulator of Wnt/beta-catenin signaling in colorectal cancer and is a therapeutic target of histone modifications.
    Cancer Cell, 13(6): 529-41. [Abstract] [Full-text]
47. MA-NOS radical sigmoidectomy: report of a transvaginal resection in the human.
    Surg Endosc, 22(7): 1717-23. [Abstract] [Full-text]
48. The malignant adenoma: when to operate and when to watch.
    Surg Endosc, 22(7): 1563-9. [Abstract] [Full-text]
49. Robotic tumor-specific mesorectal excision of rectal cancer: short-term outcome of a pilot randomized trial.
    Surg Endosc, 22(7): 1601-8. [Abstract] [Full-text]
50. Genetic deletion of mPGES-1 accelerates intestinal tumorigenesis in APC(Min/+) mice.
    Biochem Biophys Res Commun, 372(1): 249-53. [Abstract] [Full-text]
51. Morusin induces apoptosis and suppresses NF-kappaB activity in human colorectal cancer HT-29 cells.
    Biochem Biophys Res Commun, 372(1): 236-42. [Abstract] [Full-text]
52. Down-modulation of B cell signal transduction by ligation of mucins to CD22.
    Biochem Biophys Res Commun, 372(1): 45-50. [Abstract] [Full-text]
53. Are patients with skin cancer at lower risk of developing colorectal or breast cancer?
    Am J Epidemiol, 167(12): 1421-9. [Abstract] [Full-text]
54. Alcohol drinking and colorectal cancer in Japanese: a pooled analysis of results from five cohort studies.
    Am J Epidemiol, 167(12): 1397-406. [Abstract] [Full-text]
55. Activated K-RAS increases polyamine uptake in human colon cancer cells through modulation of caveolar endocytosis.
    Mol Carcinog, 47(7): 538-53. [Abstract] [Full-text]
56. Celecoxib-induced growth inhibition in SW480 colon cancer cells is associated with activation of protein kinase G.
    Mol Carcinog, 47(7): 519-25. [Abstract] [Full-text]
57. Low-dose metronomic cyclophosphamide treatment mediates ischemia-dependent K-ras mutation in colorectal carcinoma xenografts.
    Oncogene, 27(26): 3729-38. [Abstract] [Full-text]
58. Prognostic value of concomitant resection of extrahepatic disease in patients with liver metastases of colorectal origin.
    Surgery, 143(6): 706-14. [Abstract] [Full-text]
59. Intrinsically disordered human C/EBP homologous protein regulates biological activity of colon cancer cells during calcium stress.
    J Mol Biol, 380(2): 313-26. [Abstract] [Full-text]
60. Functional definition of the mutation cluster region of adenomatous polyposis coli in colorectal tumours.
    Hum Mol Genet, 17(13): 1978-87. [Abstract] [Full-text]
61. Effect of preoperative chemotherapy on liver resection for colorectal liver metastases.
    Eur J Surg Oncol, 34(7): 782-6. [Abstract] [Full-text]
62. A study of lymph node ratio as a prognostic marker in colon cancer.
    Eur J Surg Oncol, 34(7): 771-5. [Abstract] [Full-text]
63. Location of involved mesorectal and extramesorectal lymph nodes in patients with primary rectal cancer: preoperative assessment with MR imaging.
    Eur J Surg Oncol, 34(7): 776-81. [Abstract] [Full-text]
64. Association between chromosomal instability and prognosis in colorectal cancer: a meta-analysis.
    Gut, 57(7): 941-50. [Abstract] [Full-text]
65. Integrin-linked kinase regulates cell proliferation and tumour growth in murine colitis-associated carcinogenesis.
    Gut, 57(7): 931-40. [Abstract] [Full-text]
66. Sonography transmission gel as endorectal contrast agent for tumor visualization in rectal cancer.
    AJR Am J Roentgenol, 191(1): 186-9. [Abstract] [Full-text]
67. Performance of a previously validated CT colonography computer-aided detection system in a new patient population.
    AJR Am J Roentgenol, 191(1): 168-74. [Abstract] [Full-text]
68. Laparoscopic resection for colorectal cancer.
    Br J Surg, 95(7): 893-902. [Abstract] [Full-text]
69. Long-term wound advantages of the laparoscopic approach in rectal cancer.
    Br J Surg, 95(7): 903-8. [Abstract] [Full-text]
70. Reduced adhesion formation following laparoscopic versus open colorectal surgery.
    Br J Surg, 95(7): 909-14. [Abstract] [Full-text]
71. Transanal endoscopic microsurgery is a safe and reliable technique even for complex rectal lesions.
    Br J Surg, 95(7): 915-8. [Abstract] [Full-text]
72. Cost analysis of biomarker testing for mismatch repair deficiency in node-positive colorectal cancer.
    Br J Surg, 95(7): 868-75. [Abstract] [Full-text]
73. Circulating 25-hydroxyvitamin d levels and survival in patients with colorectal cancer.
    J Clin Oncol, 26(18): 2984-91. [Abstract] [Full-text]
74. A polymorphism of EGFR extracellular domain is associated with progression free-survival in metastatic colorectal cancer patients receiving cetuximab-based treatment.
    BMC Cancer, 8: 169. [Abstract] [Full-text]
75. Index-based dietary patterns and risk of colorectal cancer: the NIH-AARP Diet and Health Study.
    Am J Epidemiol, 168(1): 38-48. [Abstract] [Full-text]
76. Extracellular plasma RNA from colon cancer patients is confined in a vesicle-like structure and is mRNA-enriched.
    RNA, 14(7): 1424-32. [Abstract] [Full-text]
77. Cell-surface nucleolin is a signal transducing P-selectin binding protein for human colon carcinoma cells.
    Exp Cell Res, 314(11): 2212-23. [Abstract] [Full-text]
78. Determinants of racial/ethnic colorectal cancer screening disparities.
    Arch Intern Med, 168(12): 1317-24. [Abstract] [Full-text]
79. The association between genetic variants in hMLH1 and hMSH2 and the development of sporadic colorectal cancer in the Danish population.
    BMC Med Genet, 9: 52. [Abstract] [Full-text]
80. Systematic review and meta-analysis of the role of defunctioning stoma in low rectal cancer surgery.
    Ann Surg, 248(1): 52-60. [Abstract] [Full-text]
81. The long-term results of a randomized clinical trial of laparoscopy-assisted versus open surgery for colon cancer.
    Ann Surg, 248(1): 1-7. [Abstract] [Full-text]
82. Linoleic-acid-induced growth suppression induces quiescent cancer cell nests in nude mice.
    Pathobiology, 75(4): 226-32. [Abstract] [Full-text]
83. FOLFOX-4 regimen with concomitant highly active antiretroviral therapy in metastatic colorectal cancer HIV-infected patients: a report of five cases and review of the literature.
    Cancer Invest, 26(6): 610-4. [Abstract] [Full-text]
84. Microsatellite instability and the association with plasma homocysteine and thymidylate synthase in colorectal cancer.
    Cancer Invest, 26(6): 583-9. [Abstract] [Full-text]
85. Histone H3 (lys-9) deacetylation is associated with transcriptional silencing of E-cadherin in colorectal cancer cell lines.
    Cancer Invest, 26(6): 575-82. [Abstract] [Full-text]
86. Modification of the primary tumor microenvironment by transforming growth factor alpha-epidermal growth factor receptor signaling promotes metastasis in an orthotopic colon cancer model.
    Am J Pathol, 173(1): 205-16. [Abstract] [Full-text]
87. Regulation of Skp2-p27 axis by the Cdh1/anaphase-promoting complex pathway in colorectal tumorigenesis.
    Am J Pathol, 173(1): 217-28. [Abstract] [Full-text]
88. Accuracy of endorectal ultrasonography and computed tomography for restaging rectal cancer after preoperative chemoradiation.
    J Am Coll Surg, 207(1): 7-12. [Abstract] [Full-text]
89. Activated kRas protects colon cancer cells from cucurbitacin-induced apoptosis: the role of p53 and p21.
    Biochem Pharmacol, 76(2): 198-207. [Abstract] [Full-text]
90. The anti-proliferative potency of celecoxib is not a class effect of coxibs.
    Biochem Pharmacol, 76(2): 179-87. [Abstract] [Full-text]
91. Multidisciplinary management of colorectal brain metastases: a retrospective study.
    Cancer, 113(1): 158-65. [Abstract] [Full-text]
92. Pathologic stage is most prognostic of disease-free survival in locally advanced rectal cancer patients after preoperative chemoradiation.
    Cancer, 113(1): 57-64. [Abstract] [Full-text]

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