Colorectal Cancer Research Today is a free monthly online journal that collates and summarizes the latest research about Colorectal Cancer, including details on symptoms, genetics, screening, treatment, information.

Volume 5 (2008), Issue 5 (May)

1. Controversies of total mesorectal excision for rectal cancer in elderly patients.
   Lancet Oncol, 9(5): 494-501. [Abstract] [Full-text]
2. Lessons from the skin--cutaneous features of familial cancer.
   Lancet Oncol, 9(5): 462-72. [Abstract] [Full-text]
3. APC mutation spectrum in ileoanal pouch polyps resembles that of colorectal polyps.
   Br J Surg, 95(6): 765-9. [Abstract] [Full-text]
4. Low expression of gamma-glutamyl hydrolase mRNA in primary colorectal cancer with the CpG island methylator phenotype.
   Br J Cancer, 98(9): 1555-61. [Abstract] [Full-text]
5. Prognostic significance of VEGF expression evaluated by quantitative immunohistochemical analysis in colorectal cancer.
   J Surg Res, 147(1): 99-107. [Abstract] [Full-text]
6. Compliance, attitudes and barriers to post-operative colorectal cancer follow-up.
   J Eval Clin Pract, 14(3): 407-15. [Abstract] [Full-text]
7. Results of preoperative hepatic arterial infusion chemotherapy in patients undergoing liver resection for colorectal liver metastases.
   Ann Surg Oncol, 15(6): 1661-9. [Abstract] [Full-text]
8. Soluble intercellular adhesion molecule-1 as a prognostic marker for stage II colorectal cancer patients.
   Ann Surg Oncol, 15(6): 1617-24. [Abstract] [Full-text]
9. Laparoscopic pelvic autonomic nerve-preserving surgery for sigmoid colon cancer.
   Ann Surg Oncol, 15(6): 1609-16. [Abstract] [Full-text]
10. Lymph node ratio: role in the staging of node-positive colon cancer.
    Ann Surg Oncol, 15(6): 1600-8. [Abstract] [Full-text]
11. Survival following recurrence in stage II and III colon cancer: findings from the ACCENT data set.
    J Clin Oncol, 26(14): 2336-41. [Abstract] [Full-text]
12. Quantitative analysis of methylation of genomic loci in early-stage rectal cancer predicts distant recurrence.
    J Clin Oncol, 26(14): 2327-35. [Abstract] [Full-text]
13. Bortezomib with or without irinotecan in relapsed or refractory colorectal cancer: results from a randomized phase II study.
    J Clin Oncol, 26(14): 2320-6. [Abstract] [Full-text]
14. EPIC: phase III trial of cetuximab plus irinotecan after fluoropyrimidine and oxaliplatin failure in patients with metastatic colorectal cancer.
    J Clin Oncol, 26(14): 2311-9. [Abstract] [Full-text]
15. Involvement of 67-kDa laminin receptor-mediated myosin phosphatase activation in antiproliferative effect of epigallocatechin-3-O-gallate at a physiological concentration on Caco-2 colon cancer cells.
    Biochem Biophys Res Commun, 371(1): 172-6. [Abstract] [Full-text]
16. Concomitant colorectal cancer and abdominal aortic aneurysm: evolution of treatment paradigm in the endovascular era.
    J Am Coll Surg, 206(5): 1065-73; discussion 1074-5. [Abstract] [Full-text]
17. A prognostic system applicable to patients with resectable liver metastasis from colorectal carcinoma staged by positron emission tomography with [18F]fluoro-2-deoxy-D-glucose: role of primary tumor variables.
    J Am Coll Surg, 206(5): 857-68; discussion 868-9. [Abstract] [Full-text]
18. Deregulated expression of pro-survival and pro-apoptotic p53-dependent genes upon Elongator deficiency in colon cancer cells.
    Biochem Pharmacol, 75(11): 2122-34. [Abstract] [Full-text]
19. A phase II trial of lomeguatrib and temozolomide in metastatic colorectal cancer.
    Br J Cancer, 98(10): 1614-8. [Abstract] [Full-text]
20. Antiangiogenic and anticolorectal cancer effects of metronomic irinotecan chemotherapy alone and in combination with semaxinib.
    Br J Cancer, 98(10): 1619-29. [Abstract] [Full-text]
21. Expression of SDF-1 alpha and nuclear CXCR4 predicts lymph node metastasis in colorectal cancer.
    Br J Cancer, 98(10): 1682-9. [Abstract] [Full-text]
22. Evaluating mesorectal lymph nodes in rectal cancer before and after neoadjuvant chemoradiation using thin-section T2-weighted magnetic resonance imaging.
    Int J Radiat Oncol Biol Phys, 71(2): 456-61. [Abstract] [Full-text]
23. Downregulation of Krüppel-like factor 9 in human colorectal cancer.
    Pathol Int, 58(6): 334-8. [Abstract] [Full-text]
24. Time trends in colon cancer incidence and distribution and lower gastrointestinal endoscopy utilization in Manitoba.
    Am J Gastroenterol, 103(5): 1249-56. [Abstract] [Full-text]
25. High prevalence of Foxp3 and IL17 in MMR-proficient colorectal carcinomas.
    Gut, 57(6): 772-9. [Abstract] [Full-text]
26. Genetic and epigenetic changes in aberrant crypt foci and serrated polyps.
    Cancer Sci, 99(6): 1071-6. [Abstract] [Full-text]
27. Adjuvant chemotherapy for stage III colon cancer: do physicians agree about the importance of patient age and comorbidity?
    J Clin Oncol, 26(15): 2532-7. [Abstract] [Full-text]
28. HIV-specific differences in outcome of squamous cell carcinoma of the anal canal: a multicentric cohort study of HIV-positive patients receiving highly active antiretroviral therapy.
    J Clin Oncol, 26(15): 2550-7. [Abstract] [Full-text]
29. In vivo near-infrared fluorescence imaging of carcinoembryonic antigen-expressing tumor cells in mice.
    Radiology, 247(3): 779-87. [Abstract] [Full-text]
30. Quantitative assessment of colorectal cancer tumor vascular parameters by using perfusion CT: influence of tumor region of interest.
    Radiology, 247(3): 726-32. [Abstract] [Full-text]
31. Survival and treatment trends of rectal cancer patients in a population with suboptimal local control.
    Eur J Surg Oncol, 34(6): 655-61. [Abstract] [Full-text]
32. A prospective comparison study for predicting circumferential resection margin between preoperative MRI and whole mount sections in mid-rectal cancer: significance of different scan planes.
    Eur J Surg Oncol, 34(6): 648-54. [Abstract] [Full-text]
33. The implications of genetic susceptibility for the prevention of colorectal cancer: a qualitative study of older adults' understanding.
    Community Genet, 11(5): 283-8. [Abstract] [Full-text]
34. Perspective on the role of transrectal and transvaginal sonography of tumors of the rectum and anal canal.
    AJR Am J Roentgenol, 190(6): 1495-504. [Abstract] [Full-text]
35. Residual treatment disparities after oncology referral for rectal cancer.
    J Natl Cancer Inst, 100(10): 738-44. [Abstract] [Full-text]
36. Characterization of HCT116 human colon cancer cells in an orthotopic model.
    J Surg Res, 147(2): 276-81. [Abstract] [Full-text]
37. Does surgeon case volume influence nonfatal adverse outcomes after rectal cancer resection?
    J Am Coll Surg, 206(3): 1167-77. [Abstract] [Full-text]
38. Colonic crypt organization and tumorigenesis.
    Nat Rev Cancer, 8(6): 415-24. [Abstract] [Full-text]
39. c-Met gene amplification is associated with advanced stage colorectal cancer and liver metastases.
    Cancer Lett, 265(2): 258-69. [Abstract] [Full-text]
40. Mitotic centromere-associated kinesin is a novel marker for prognosis and lymph node metastasis in colorectal cancer.
    Br J Cancer, 98(11): 1824-9. [Abstract] [Full-text]
41. MMP-2 geno-phenotype is prognostic for colorectal cancer survival, whereas MMP-9 is not.
    Br J Cancer, 98(11): 1820-3. [Abstract] [Full-text]
42. SPARC promoter hypermethylation in colorectal cancers can be reversed by 5-Aza-2'deoxycytidine to increase SPARC expression and improve therapy response.
    Br J Cancer, 98(11): 1810-9. [Abstract] [Full-text]
43. Predictive biomarkers of chemotherapy efficacy in colorectal cancer: results from the UK MRC FOCUS trial.
    J Clin Oncol, 26(16): 2690-8. [Abstract] [Full-text]
44. P53 mutations in colorectal cancer from northern Iran: Relationships with site of tumor origin, microsatellite instability and K-ras mutations.
    J Cell Physiol, 216(2): 543-50. [Abstract] [Full-text]
45. Carcinoma of unknown primary with a colon-cancer profile-changing paradigm and emerging definitions.
    Lancet Oncol, 9(6): 596-9. [Abstract] [Full-text]
46. Individual tumorigenesis pathways of sporadic colorectal adenocarcinomas are associated with the biological behavior of tumors.
    Cancer Sci, 99(7): 1348-54. [Abstract] [Full-text]

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