Colorectal Cancer Research Today is a free monthly online journal that collates and summarizes the latest research about Colorectal Cancer, including details on symptoms, genetics, screening, treatment, information.

Volume 5 (2008), Issue 2 (February)

1. Cancer proliferation gene discovery through functional genomics.
   Science, 319(5863): 620-4. [Abstract] [Full-text]
2. Desmoid tumors in a dutch cohort of patients with familial adenomatous polyposis.
   Clin Gastroenterol Hepatol, 6(2): 215-9. [Abstract] [Full-text]
3. Fundic gland polyp dysplasia is common in familial adenomatous polyposis.
   Clin Gastroenterol Hepatol, 6(2): 180-5. [Abstract] [Full-text]
4. A prospective, multicenter, population-based study of BRAF mutational analysis for Lynch syndrome screening.
   Clin Gastroenterol Hepatol, 6(2): 206-14. [Abstract] [Full-text]
5. Pelvic phased-array MR imaging of anal carcinoma before and after chemoradiation.
   Br J Radiol, 81(962): 91-8. [Abstract] [Full-text]
6. Silencing of human ferrochelatase causes abundant protoporphyrin-IX accumulation in colon cancer.
   FASEB J, 22(2): 500-9. [Abstract] [Full-text]
7. Culture-independent analysis of the gut microbiota in colorectal cancer and polyposis.
   Environ Microbiol, 10(3): 789-98. [Abstract] [Full-text]
8. Cigarette smoking and adenomatous polyps: a meta-analysis.
   Gastroenterology, 134(2): 388-95. [Abstract] [Full-text]
9. Local excision and transanal endoscopic microsurgery in the management of rectal cancer with a focus on early carcinoma.
   Future Oncol, 4(1): 113-24. [Abstract] [Full-text]
10. DR5 receptor mediates anoikis in human colorectal carcinoma cell lines.
    Cancer Res, 68(3): 909-17. [Abstract] [Full-text]
11. Epitope landscape in breast and colorectal cancer.
    Cancer Res, 68(3): 889-92. [Abstract] [Full-text]
12. Systematic high-content proteomic analysis reveals substantial immunologic changes in colorectal cancer.
    Cancer Res, 68(3): 880-8. [Abstract] [Full-text]
13. Role of hepatectomy in treating multiple bilobar colorectal cancer metastases.
    Surgery, 143(2): 259-70. [Abstract] [Full-text]
14. Toward understanding nonparticipation in sigmoidoscopy screening for colorectal cancer.
    Int J Cancer, 122(7): 1618-23. [Abstract] [Full-text]
15. Leptin and leptin receptor genotypes and colon cancer: gene-gene and gene-lifestyle interactions.
    Int J Cancer, 122(7): 1611-7. [Abstract] [Full-text]
16. HPP1-mediated tumor suppression requires activation of STAT1 pathways.
    Int J Cancer, 122(7): 1567-72. [Abstract] [Full-text]
17. Marked regression of liver metastasis by combined therapy of ultrasound-mediated NF kappaB-decoy transfer and transportal injection of paclitaxel, in mouse.
    Int J Cancer, 122(7): 1645-56. [Abstract] [Full-text]
18. The expression of low molecular weight protein tyrosine phosphatase is up-regulated in 1,2-dimethylhydrazine-induced colon tumours in rats.
    Int J Cancer, 122(7): 1675-8. [Abstract] [Full-text]
19. Clustering of Lynch syndrome malignancies with no evidence for a role of DNA mismatch repair.
    Gynecol Oncol, 108(2): 438-44. [Abstract] [Full-text]
20. Blocking alpha2 integrins on rat CC531s colon carcinoma cells prevents operation-induced augmentation of liver metastases outgrowth.
    Hepatology, 47(2): 532-43. [Abstract] [Full-text]
21. Community-based preferences for stool cards versus colonoscopy in colorectal cancer screening.
    J Gen Intern Med, 23(2): 169-74. [Abstract] [Full-text]
22. Beliefs, risk perceptions, and gaps in knowledge as barriers to colorectal cancer screening in older adults.
    J Am Geriatr Soc, 56(2): 307-14. [Abstract] [Full-text]
23. A role for iron in Wnt signalling.
    Oncogene, 27(7): 966-75. [Abstract] [Full-text]
24. Effects of carrot and tomato juice consumption on faecal markers relevant to colon carcinogenesis in humans.
    Br J Nutr, 99(3): 606-13. [Abstract] [Full-text]
25. Non-Hodgkin lymphoma related to hereditary nonpolyposis colorectal cancer in a patient with a novel heterozygous complex deletion in the MSH2 gene.
    Genes Chromosomes Cancer, 47(4): 326-32. [Abstract] [Full-text]
26. Persistent elevation of plasma vascular endothelial growth factor levels during the first month after minimally invasive colorectal resection.
    Surg Endosc, 22(2): 287-97. [Abstract] [Full-text]
27. Standardized technique of laparoscopic intracorporeal rectal transection and anastomosis for low anterior resection.
    Surg Endosc, 22(2): 557-61. [Abstract] [Full-text]
28. Neoadjuvant chemoradiation and local excision for T2-3 rectal cancer.
    Ann Surg Oncol, 15(3): 712-20. [Abstract] [Full-text]
29. Improving rates for screening colonoscopy: Analysis of the health information national trends survey (HINTS I) data.
    Surg Endosc, 22(2): 527-33. [Abstract] [Full-text]
30. Factors influencing pathologic results after total mesorectal excision for rectal cancer: analysis of consecutive 100 cases.
    Ann Surg Oncol, 15(3): 721-8. [Abstract] [Full-text]
31. Lateral lymph node metastasis is a major cause of locoregional recurrence in rectal cancer treated with preoperative chemoradiotherapy and curative resection.
    Ann Surg Oncol, 15(3): 729-37. [Abstract] [Full-text]
32. A novel method to localize antibody-targeted cancer deposits intraoperatively using handheld PET beta and gamma probes.
    Surg Endosc, 22(2): 386-91. [Abstract] [Full-text]
33. A prospective randomized study with a 5-year minimum follow-up evaluation of transanal endoscopic microsurgery versus laparoscopic total mesorectal excision after neoadjuvant therapy.
    Surg Endosc, 22(2): 352-8. [Abstract] [Full-text]
34. Positron emission tomography detection of distant metastatic or synchronous disease in patients with locally advanced rectal cancer receiving preoperative chemoradiation.
    Ann Surg Oncol, 15(3): 704-11. [Abstract] [Full-text]
35. The usefulness of preoperative colonoscopic tattooing using a saline test injection method with prepackaged sterile India ink for localization in laparoscopic colorectal surgery.
    Surg Endosc, 22(2): 501-5. [Abstract] [Full-text]
36. Laparoscopic colectomy for apparently benign colorectal neoplasia: A word of caution.
    Surg Endosc, 22(2): 506-9. [Abstract] [Full-text]
37. Intraoperative fluoroscopy vs. intraoperative laparoscopic ultrasonography for early colorectal cancer localization in laparoscopic surgery.
    Surg Endosc, 22(2): 379-85. [Abstract] [Full-text]
38. Carboxylesterase 2 is downregulated in colorectal cancer following progression of the disease.
    Cancer Invest, 26(2): 178-81. [Abstract] [Full-text]
39. Radiotherapy for rectal cancer is associated with reduced serum testosterone and increased FSH and LH.
    Int J Radiat Oncol Biol Phys, 70(3): 722-7. [Abstract] [Full-text]
40. Protective effects of vanadium against DMH-induced genotoxicity and carcinogenesis in rat colon: removal of O(6)-methylguanine DNA adducts, p53 expression, inducible nitric oxide synthase downregulation and apoptotic induction.
    Mutat Res, 650(2): 123-31. [Abstract] [Full-text]
41. Soybean saponin inhibits tumor cell metastasis by modulating expressions of MMP-2, MMP-9 and TIMP- 2.
    Cancer Lett, 261(1): 84-92. [Abstract] [Full-text]
42. Phase II study of preoperative helical tomotherapy for rectal cancer.
    Int J Radiat Oncol Biol Phys, 70(3): 728-34. [Abstract] [Full-text]
43. Genome-wide tracking of unmethylated DNA Alu repeats in normal and cancer cells.
    Nucleic Acids Res, 36(3): 770-84. [Abstract] [Full-text]
44. Protein kinase G as a therapeutic target for the treatment of metastatic colorectal cancer.
    Expert Opin Ther Targets, 12(3): 367-76. [Abstract] [Full-text]
45. The apoptosis-inducing effect of gastrin on colorectal cancer cells relates to an increased IEX-1 expression mediating NF-kappa B inhibition.
    Oncogene, 27(8): 1122-34. [Abstract] [Full-text]
46. Poorly differentiated colorectal adenocarcinomas show higher rates of microsatellite instability and promoter methylation of p16 and hMLH1: a study matched for T classification and tumor location.
    J Surg Oncol, 97(3): 278-83. [Abstract] [Full-text]
47. Cetuximab shows activity in colorectal cancer patients with tumors for which FISH analysis does not detect an increase in EGFR gene copy number.
    Ann Surg Oncol, 15(2): 649-54. [Abstract] [Full-text]
48. Effect of adjuvant radiotherapy on local recurrence in stage II rectal cancer.
    Ann Surg Oncol, 15(2): 519-25. [Abstract] [Full-text]
49. Biological and genetic characteristics of tumor-initiating cells in colon cancer.
    Ann Surg Oncol, 15(2): 638-48. [Abstract] [Full-text]
50. Analysis of centrosome overduplication in correlation to cell division errors in high-risk human papillomavirus (HPV)-associated anal neoplasms.
    Virology, 372(1): 157-64. [Abstract] [Full-text]
51. Perceptions of cancer risks and predictors of colon and endometrial cancer screening in women undergoing genetic testing for Lynch syndrome.
    J Clin Oncol, 26(6): 948-54. [Abstract] [Full-text]
52. Association of genetic variation in the transforming growth factor beta-1 gene with serum levels and risk of colorectal neoplasia.
    Cancer Res, 68(4): 1236-44. [Abstract] [Full-text]
53. Cyclooxygenase-2 inhibition inhibits c-Met kinase activity and Wnt activity in colon cancer.
    Cancer Res, 68(4): 1213-20. [Abstract] [Full-text]
54. Efficient identification of a novel cancer/testis antigen for immunotherapy using three-step microarray analysis.
    Cancer Res, 68(4): 1074-82. [Abstract] [Full-text]
55. Trends in follow-up and preventive care for colorectal cancer survivors.
    J Gen Intern Med, 23(3): 254-9. [Abstract] [Full-text]
56. p53 Nuclear accumulation and Bcl-2 expression in contiguous adenomatous components of colorectal adenocarcinomas predict aggressive tumor behavior.
    J Histochem Cytochem, 56(3): 305-12. [Abstract] [Full-text]
57. Influence of subclinical tumor spreading on survival after curative surgery for colorectal cancer.
    Arch Surg, 143(2): 122-8. [Abstract] [Full-text]
58. Rapid identification of somatic mutations in colorectal and breast cancer tissues using mismatch repair detection (MRD).
    Hum Mutat, 29(3): 441-50. [Abstract] [Full-text]
59. Somatic FGF9 mutations in colorectal and endometrial carcinomas associated with membranous beta-catenin.
    Hum Mutat, 29(3): 390-7. [Abstract] [Full-text]
60. Classification of ambiguous mutations in DNA mismatch repair genes identified in a population-based study of colorectal cancer.
    Hum Mutat, 29(3): 367-74. [Abstract] [Full-text]
61. The frequency of Muir-Torre syndrome among Lynch syndrome families.
    J Natl Cancer Inst, 100(4): 277-81. [Abstract] [Full-text]
62. Chronopharmacokinetics of oral tegafur and uracil in colorectal cancer patients.
    Clin Pharmacol Ther, 83(3): 413-5. [Abstract] [Full-text]
63. Frequent beta-catenin nuclear labeling in sessile serrated polyps of the colorectum with neoplastic potential.
    Am J Clin Pathol, 129(3): 416-23. [Abstract] [Full-text]
64. Cell growth, global phosphotyrosine elevation, and c-Met phosphorylation through Src family kinases in colorectal cancer cells.
    Proc Natl Acad Sci U S A, 105(7): 2358-62. [Abstract] [Full-text]
65. Intertriginous plasmacytosis with plasmoacanthoma: report of a typical case and review of the literature.
    Int J Dermatol, 47(3): 265-8. [Abstract] [Full-text]
66. Local excision and endoscopic posterior mesorectal resection versus low anterior resection in T1 rectal cancer.
    Br J Surg, 95(3): 375-80. [Abstract] [Full-text]
67. Assessment of a patient consultation questionnaire-based scoring system for stratification of outpatient risk of colorectal cancer.
    Br J Surg, 95(3): 369-74. [Abstract] [Full-text]
68. Automated carbon dioxide insufflation for CT colonography: effectiveness of colonic distention in cancer patients with severe luminal narrowing.
    AJR Am J Roentgenol, 190(3): 698-706. [Abstract] [Full-text]
69. Outcomes for women in a flexible sigmoidoscopy-based colorectal cancer screening programme.
    Intern Med J, 38(2): 90-4. [Abstract] [Full-text]
70. Influence of surgical margin on type of recurrence after liver resection for colorectal metastases: a single-center experience.
    Surgery, 143(3): 384-93. [Abstract] [Full-text]
71. Chemoradiotherapy followed by surgery in rectal cancer: improved local control using a moderately high pelvic radiation dose.
    Jpn J Clin Oncol, 38(2): 112-21. [Abstract] [Full-text]
72. Multimarker phenotype predicts adverse survival in patients with lymph node-negative colorectal cancer.
    Cancer, 112(3): 495-502. [Abstract] [Full-text]
73. Antitumor activity of 3,5,4'-trimethoxystilbene in COLO 205 cells and xenografts in SCID mice.
    Mol Carcinog, 47(3): 184-96. [Abstract] [Full-text]
74. Multiple mechanisms are involved in 6-gingerol-induced cell growth arrest and apoptosis in human colorectal cancer cells.
    Mol Carcinog, 47(3): 197-208. [Abstract] [Full-text]
75. Serum amyloid A enhances plasminogen activation: implication for a role in colon cancer.
    Biochem Biophys Res Commun, 368(2): 368-73. [Abstract] [Full-text]
76. Induction of colitis and rapid development of colorectal tumors in mice deficient in the neuropeptide PACAP.
    Int J Cancer, 122(8): 1803-9. [Abstract] [Full-text]
77. Fra-1 regulates vimentin during Ha-RAS-induced epithelial mesenchymal transition in human colon carcinoma cells.
    Int J Cancer, 122(8): 1745-56. [Abstract] [Full-text]
78. Interaction of estrogen therapy with calcium and vitamin D supplementation on colorectal cancer risk: reanalysis of Women's Health Initiative randomized trial.
    Int J Cancer, 122(8): 1690-4. [Abstract] [Full-text]
79. Nox1 downstream of 12-lipoxygenase controls cell proliferation but not cell spreading of colon cancer cells.
    Int J Cancer, 122(8): 1757-64. [Abstract] [Full-text]
80. Colorectal cancer cells express functional cell surface-bound TGFbeta.
    Int J Cancer, 122(8): 1695-700. [Abstract] [Full-text]
81. Familial clustering of cancer at human papillomavirus-associated sites according to the Swedish Family-Cancer Database.
    Int J Cancer, 122(8): 1873-8. [Abstract] [Full-text]
82. NQO1 and NFE2L2 polymorphisms, fruit and vegetable intake and smoking and the risk of colorectal adenomas in an endoscopy-based population.
    Int J Cancer, 122(8): 1842-8. [Abstract] [Full-text]
83. Carob fibre compounds modulate parameters of cell growth differently in human HT29 colon adenocarcinoma cells than in LT97 colon adenoma cells.
    Food Chem Toxicol, 46(4): 1389-97. [Abstract] [Full-text]
84. Clinical impact of HLA class I expression in rectal cancer.
    Cancer Immunol Immunother, 57(5): 601-9. [Abstract] [Full-text]
85. Three-dimensional endoluminal ultrasound-guided interstitial brachytherapy in patients with anal cancer.
    Acta Radiol, 49(2): 132-7. [Abstract] [Full-text]
86. Deoxycholyltaurine rescues human colon cancer cells from apoptosis by activating EGFR-dependent PI3K/Akt signaling.
    J Cell Physiol, 215(2): 538-49. [Abstract] [Full-text]
87. KRAS wild-type state predicts survival and is associated to early radiological response in metastatic colorectal cancer treated with cetuximab.
    Ann Oncol, 19(3): 508-15. [Abstract] [Full-text]
88. Relationship between LAPTM4B gene polymorphism and susceptibility of colorectal and esophageal cancers.
    Ann Oncol, 19(3): 527-32. [Abstract] [Full-text]
89. Combination of sensitizing pretreatment and radiofrequency tumor ablation: evaluation in rat model.
    Radiology, 246(3): 796-803. [Abstract] [Full-text]
90. Clinical results of intraoperative radiation therapy for patients with locally recurrent and advanced tumors having colorectal involvement.
    Am J Surg, 195(3): 405-9. [Abstract] [Full-text]
91. Colorectal cancer surgery in the elderly: acceptable morbidity?
    Am J Surg, 195(3): 344-8; discussion 348. [Abstract] [Full-text]
92. USPIO-enhanced MR imaging for nodal staging in patients with primary rectal cancer: predictive criteria.
    Radiology, 246(3): 804-11. [Abstract] [Full-text]

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