Colorectal Cancer Research Today is a free monthly online journal that collates and summarizes the latest research about Colorectal Cancer, including details on symptoms, genetics, screening, treatment, information.

Malignancy risk of small polyps and related factors.

Unal H, Selcuk H, Gokcan H, Tore E, Sar A, Korkmaz M, Bilezikci B, Demirhan B, Gur G, Yilmaz U

Department of Gastroenterology, Baskent University, 10 sok No. 45, Bahcelievler, Ankara, 06450, Turkey.

The aim of this study was to determine the risk of polyps <6 and between 6 and 10 mm in terms of progression to malignancy and to evaluate the influence of age, gender, and colonic localization on malignancy development. Thirteen hundred sixty-nine polyps <10 mm identified in 680 patients were retrospectively evaluated. Sixty-seven and two-tenths percent of polyps <10 mm were of a neoplastic nature. The incidence of neoplasia was higher in left-sided and small polyps than diminutive polyps. In patients older than 60 years, small polyps showed a higher rate of high-risk histology than diminutive polyps,while the same relationship did not exist in other age groups. In male patients over 60 years of age, the rate of high-risk histology was higher in small polyps than in diminutive polyps.

Published 6 September 2007 in Dig Dis Sci, 52(10): 2796-9.
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