Colorectal Cancer Research Today is a free monthly online journal that collates and summarizes the latest research about Colorectal Cancer, including details on symptoms, genetics, screening, treatment, information.

Volume 4 (2007), Issue 3 (March)

1. Functional imaging of colorectal cancer angiogenesis.
   Lancet Oncol, 8(3): 245-55. [Abstract] [Full-text]
2. Basement membrane component laminin-5 is a target of the tumor suppressor Smad4.
   Oncogene, 26(10): 1417-27. [Abstract] [Full-text]
3. High-resolution copy number analysis of paraffin-embedded archival tissue using SNP BeadArrays.
   Genome Res, 17(3): 368-76. [Abstract] [Full-text]
4. Risk perception, worry and satisfaction related to genetic counseling for hereditary cancer.
   J Genet Couns, 16(2): 211-22. [Abstract] [Full-text]
5. Phase II study of interleukin-2 and 13-cis-retinoic acid as maintenance therapy in metastatic colorectal cancer.
   Cancer Immunol Immunother, 56(5): 699-708. [Abstract] [Full-text]
6. HNPCC versus sporadic microsatellite-unstable colon cancers follow different routes toward loss of HLA class I expression.
   BMC Cancer, 7: 33. [Abstract] [Full-text]
7. Rectal cancer delivery of radiotherapy in adequate time and with adequate dose is influenced by treatment center, treatment schedule, and gender and is prognostic parameter for local control: results of study CAO/ARO/AIO-94.
   Int J Radiat Oncol Biol Phys, 67(4): 1008-19. [Abstract] [Full-text]
8. Optimal time interval between capecitabine intake and radiotherapy in preoperative chemoradiation for locally advanced rectal cancer.
   Int J Radiat Oncol Biol Phys, 67(4): 1020-6. [Abstract] [Full-text]
9. Genomic rearrangements in MSH2, MLH1 or MSH6 are rare in HNPCC patients carrying point mutations.
   Cancer Lett, 248(1): 89-95. [Abstract] [Full-text]
10. Drug insight: aminosalicylates for the treatment of IBD.
    Nat Clin Pract Gastroenterol Hepatol, 4(3): 160-70. [Abstract] [Full-text]
11. A prospective comparative study of narrow-band imaging, chromoendoscopy, and conventional colonoscopy in the diagnosis of colorectal neoplasia.
    Gut, 56(3): 373-9. [Abstract] [Full-text]
12. Human colorectal mucosal O6-alkylguanine DNA-alkyltransferase activity and DNA-N7-methylguanine levels in colorectal adenoma cases and matched referents.
    Gut, 56(3): 380-4. [Abstract] [Full-text]
13. Tissue-specific differential antitumour effect of molecular forms of fractalkine in a mouse model of metastatic colon cancer.
    Gut, 56(3): 365-72. [Abstract] [Full-text]
14. Aberrant crypt foci in patients with a positive family history of sporadic colorectal cancer.
    Cancer Lett, 248(2): 262-8. [Abstract] [Full-text]
15. Molecular co-expression of the c-Met oncogene and hepatocyte growth factor in primary colon cancer predicts tumor stage and clinical outcome.
    Cancer Lett, 248(2): 219-28. [Abstract] [Full-text]
16. Modeling survival in colon cancer: a methodological review.
    Mol Cancer, 6: 15. [Abstract] [Full-text]
17. Transforming growth factor-[beta]1 -509T reduces risk of colorectal cancer, but not adenoma in Koreans.
    Cancer Sci, 98(3): 401-4. [Abstract] [Full-text]
18. Overexpression of soluble vascular endothelial growth factor receptor 1 in colorectal cancer: Association with progression and prognosis.
    Cancer Sci, 98(3): 405-10. [Abstract] [Full-text]
19. Development and characterization of novel photosensitizer : scFv conjugates for use in photodynamic therapy of cancer.
    Immunology, 120(4): 512-7. [Abstract] [Full-text]
20. Evidence for the role of aberrant DNA methylation in the pathogenesis of Lynch syndrome adenomas.
    Int J Cancer, 120(9): 1922-9. [Abstract] [Full-text]
21. Plasma C-peptide, insulin-like growth factor-I, insulin-like growth factor binding proteins and risk of colorectal cancer in a nested case-control study: the Japan public health center-based prospective study.
    Int J Cancer, 120(9): 2007-12. [Abstract] [Full-text]
22. The high prevalence of colorectal neoplasms in preoperative patients with abdominal aortic aneurysm or peripheral artery disease.
    Eur J Vasc Endovasc Surg, 33(4): 397-400. [Abstract] [Full-text]
23. Organ preservation for rectal cancer.
    J Clin Oncol, 25(8): 1014-20. [Abstract] [Full-text]
24. Allelic losses at genomic instability-associated loci in villous adenomas and adjacent colorectal cancers.
    Cancer Genet Cytogenet, 174(1): 9-15. [Abstract] [Full-text]
25. Development of a risk score for colorectal cancer in men.
    Am J Med, 120(3): 257-63. [Abstract] [Full-text]
26. The TKTL1 gene influences total transketolase activity and cell proliferation in human colon cancer LoVo cells.
    Anticancer Drugs, 18(4): 427-33. [Abstract] [Full-text]
27. Consumption of prebiotic inulin enriched with oligofructose in combination with the probiotics Lactobacillus rhamnosus and Bifidobacterium lactis has minor effects on selected immune parameters in polypectomised and colon cancer patients.
    Br J Nutr, 97(4): 676-84. [Abstract] [Full-text]
28. Liver regeneration stimulates tumor metastases.
    J Surg Res, 138(2): 284-90. [Abstract] [Full-text]
29. Effects of a tailored interactive multimedia computer program on determinants of colorectal cancer screening: a randomized controlled pilot study in physician offices.
    Patient Educ Couns, 66(1): 67-74. [Abstract] [Full-text]
30. Physician colorectal cancer screening recommendations: an examination based on informed decision making.
    Patient Educ Couns, 66(1): 43-50. [Abstract] [Full-text]
31. Plasma membrane Ca2+-ATPase expression during colon cancer cell line differentiation.
    Biochem Biophys Res Commun, 355(4): 932-6. [Abstract] [Full-text]
32. Evidence for heritable predisposition to epigenetic silencing of MLH1.
    Int J Cancer, 120(8): 1684-8. [Abstract] [Full-text]
33. Prediction of chemotherapeutic response of colorectal liver metastases with dynamic gadolinium-DTPA-enhanced MRI and localized 19F MRS pharmacokinetic studies of 5-fluorouracil.
    NMR Biomed, 20(2): 128-40. [Abstract] [Full-text]
34. Oral contraceptives, reproductive factors, and risk of colorectal cancer among women in a prospective cohort study.
    Am J Epidemiol, 165(7): 794-801. [Abstract] [Full-text]
35. Calcium and vitamin D intake and risk of colorectal cancer: the Multiethnic Cohort Study.
    Am J Epidemiol, 165(7): 784-93. [Abstract] [Full-text]
36. Objective risk, subjective risk, and colorectal cancer screening among a clinic sample.
    Psychol Health Med, 12(2): 135-47. [Abstract] [Full-text]
37. Therapy of established tumors in a novel murine model transgenic for human carcinoembryonic antigen and HLA-A2 with a combination of anti-idiotype vaccine and CTL peptides of carcinoembryonic antigen.
    Cancer Res, 67(6): 2881-92. [Abstract] [Full-text]
38. Warm hepatic ischemia-reperfusion promotes growth of colorectal carcinoma micrometastases in mouse liver via matrix metalloproteinase-9 induction.
    Cancer Res, 67(6): 2720-8. [Abstract] [Full-text]
39. Oncogenic activation of the RAS/RAF signaling pathway impairs the response of metastatic colorectal cancers to anti-epidermal growth factor receptor antibody therapies.
    Cancer Res, 67(6): 2643-8. [Abstract] [Full-text]
40. Activation of tumor-specific splice variant Rac1b by dishevelled promotes canonical Wnt signaling and decreased adhesion of colorectal cancer cells.
    Cancer Res, 67(6): 2469-79. [Abstract] [Full-text]
41. A prospective randomized comparison of two instruments for dissection and vessel sealing in laparoscopic colorectal surgery.
    Surg Endosc, 21(4): 592-4. [Abstract] [Full-text]
42. Radioembolization of liver metastases from colorectal cancer using yttrium-90 microspheres with concomitant systemic oxaliplatin, fluorouracil, and leucovorin chemotherapy.
    J Clin Oncol, 25(9): 1099-106. [Abstract] [Full-text]
43. From cancer families to HNPCC: Henry Lynch and the transformations of hereditary cancer, 1975-1999.
    Bull Hist Med, 81(1): 267-85. [Abstract] [Full-text]
44. FDG PET in preoperative assessment of colorectal liver metastases combining "evidence-based practice" and "technology assessment" methods to develop departmental imaging protocols: should FDG PET be routinely used in the preoperative assessment of patients with colorectal liver metastases?
    Acad Radiol, 14(4): 389-97. [Abstract] [Full-text]
45. Recommendations for the reporting of surgically resected specimens of colorectal carcinoma.
    Hum Pathol, 38(4): 537-545. [Abstract] [Full-text]
46. TGFBR2 mutation is correlated with CpG island methylator phenotype in microsatellite instability-high colorectal cancer.
    Hum Pathol, 38(4): 614-20. [Abstract] [Full-text]
47. Cytoplasmic localization of p27 (cyclin-dependent kinase inhibitor 1B/KIP1) in colorectal cancer: inverse correlations with nuclear p27 loss, microsatellite instability, and CpG island methylator phenotype.
    Hum Pathol, 38(4): 585-92. [Abstract] [Full-text]
48. Screening patients with a family history of colorectal cancer.
    J Gen Intern Med, 22(4): 508-13. [Abstract] [Full-text]
49. Applications of nanoparticles to diagnostics and therapeutics in colorectal cancer.
    Trends Biotechnol, 25(4): 145-52. [Abstract] [Full-text]
50. Capecitabine improves cancer cachexia and normalizes IL-6 and PTHrP levels in mouse cancer cachexia models.
    Cancer Chemother Pharmacol, 59(6): 807-15. [Abstract] [Full-text]
51. Chemosensitization and radiosensitization of human lung and colon cancers by antimitotic agent, ABT-751, in athymic murine xenograft models of subcutaneous tumor growth.
    Cancer Chemother Pharmacol, 59(6): 725-32. [Abstract] [Full-text]
52. MLH1 -93G>A promoter polymorphism and the risk of microsatellite-unstable colorectal cancer.
    J Natl Cancer Inst, 99(6): 463-74. [Abstract] [Full-text]
53. Lymph node evaluation and survival after curative resection of colon cancer: systematic review.
    J Natl Cancer Inst, 99(6): 433-41. [Abstract] [Full-text]
54. Biological therapy update in colorectal cancer.
    Expert Opin Biol Ther, 7(4): 509-19. [Abstract] [Full-text]
55. Predicting response of colorectal hepatic metastasis: value of pretreatment apparent diffusion coefficients.
    AJR Am J Roentgenol, 188(4): 1001-8. [Abstract] [Full-text]
56. Flat colorectal neoplasms: definition, importance, and visualization on CT colonography.
    AJR Am J Roentgenol, 188(4): 953-9. [Abstract] [Full-text]
57. Characteristics of advanced adenomas detected at CT colonographic screening: implications for appropriate polyp size thresholds for polypectomy versus surveillance.
    AJR Am J Roentgenol, 188(4): 940-4. [Abstract] [Full-text]
58. Effect of ACE inhibitors and angiotensin II receptor antagonists in a mouse model of colorectal cancer liver metastases.
    J Gastroenterol Hepatol, 22(4): 577-84. [Abstract] [Full-text]
59. Performance characteristics and comparison of two fecal occult blood tests in patients undergoing colonoscopy.
    Dig Dis Sci, 52(4): 1009-13. [Abstract] [Full-text]
60. Using clinical audit, qualitative data from patients and feedback from general practitioners to decrease delay in the referral of suspected colorectal cancer.
    J Eval Clin Pract, 13(2): 310-7. [Abstract] [Full-text]
61. Down-regulation of PGE2 by physiologic levels of celecoxib is not sufficient to induce apoptosis or inhibit cell proliferation in human colon carcinoma cell lines.
    Dig Dis Sci, 52(4): 1128-33. [Abstract] [Full-text]
62. Minimally invasive biomarkers for detection and staging of colorectal cancer.
    Cancer Lett, 249(1): 87-96. [Abstract] [Full-text]
63. Rectal GIST presenting as a submucosal calculus.
    Dig Dis Sci, 52(4): 1047-9. [Abstract] [Full-text]
64. Use of an oncolytic virus secreting GM-CSF as combined oncolytic and immunotherapy for treatment of colorectal and hepatic adenocarcinomas.
    Surgery, 141(4): 520-9. [Abstract] [Full-text]
65. Perioperative prophylaxis with granulocyte colony-stimulating factor (G-CSF) in high-risk colorectal cancer patients for an improved recovery: A randomized, controlled trial.
    Surgery, 141(4): 501-10. [Abstract] [Full-text]
66. Bevacizumab in the treatment of metastatic colorectal cancer.
    Future Oncol, 3(2): 141-8. [Abstract] [Full-text]
67. Retrorectal cyst hamartoma (tailgut cyst) with malignant transformation.
    Gynecol Oncol, 105(1): 266-8. [Abstract] [Full-text]
68. Metabolism of a heterocyclic amine colon carcinogen in young and old rats.
    Drug Metab Dispos, 35(4): 633-9. [Abstract] [Full-text]
69. Applying projective techniques to formative research in health communication development.
    Health Promot Pract, 8(2): 164-72. [Abstract] [Full-text]
70. Selected fruits reduce azoxymethane (AOM)-induced aberrant crypt foci (ACF) in Fisher 344 male rats.
    Food Chem Toxicol, 45(5): 725-32. [Abstract] [Full-text]
71. Involvement of Ras/Raf-1/ERK actions in the magnolol-induced upregulation of p21 and cell-cycle arrest in colon cancer cells.
    Mol Carcinog, 46(4): 275-83. [Abstract] [Full-text]
72. Celecoxib inhibits the expression of survivin via the suppression of promoter activity in human colon cancer cells.
    Biochem Pharmacol, 73(9): 1318-29. [Abstract] [Full-text]
73. Association between Aurora-A kinase polymorphisms and age of onset of hereditary nonpolyposis colorectal cancer in a Caucasian population.
    Mol Carcinog, 46(4): 249-56. [Abstract] [Full-text]
74. Retinol decreases beta-catenin protein levels in retinoic acid-resistant colon cancer cell lines.
    Mol Carcinog, 46(4): 315-29. [Abstract] [Full-text]
75. Turcot syndrome confirmed with molecular analysis.
    Eur J Neurol, 14(4): 470-2. [Abstract] [Full-text]
76. Manganese superoxide dismutase (SOD2)-mediated delayed radioprotection induced by the free thiol form of amifostine and tumor necrosis factor alpha.
    Radiat Res, 167(4): 465-74. [Abstract] [Full-text]
77. Gefitinib and irinotecan in patients with fluoropyrimidine-refractory, irinotecan-naive advanced colorectal cancer: a phase I-II study.
    Ann Oncol, 18(4): 730-7. [Abstract] [Full-text]
78. A double-blind placebo-controlled randomized study of Chinese herbal medicine as complementary therapy for reduction of chemotherapy-induced toxicity.
    Ann Oncol, 18(4): 768-74. [Abstract] [Full-text]
79. A phase IB, open-label dose-escalating study of the oral angiogenesis inhibitor PTK787/ZK 222584 (PTK/ZK), in combination with FOLFOX4 chemotherapy in patients with advanced colorectal cancer.
    Ann Oncol, 18(4): 782-8. [Abstract] [Full-text]
80. Phase I/II study of preoperative cetuximab, capecitabine, and external beam radiotherapy in patients with rectal cancer.
    Ann Oncol, 18(4): 738-44. [Abstract] [Full-text]
81. Pulmonary radiofrequency ablation: long-term safety and efficacy in 153 patients.
    Radiology, 243(1): 268-75. [Abstract] [Full-text]
82. Perinecrotic hypoxia contributes to ischemia/reperfusion-accelerated outgrowth of colorectal micrometastases.
    Am J Pathol, 170(4): 1379-88. [Abstract] [Full-text]
83. P2Y2- and P2Y4 purinergic receptors are over-expressed in human colon cancer.
    Auton Autacoid Pharmacol, 27(2): 79-84. [Abstract] [Full-text]
84. MR colonography with limited bowel preparation compared with optical colonoscopy in patients at increased risk for colorectal cancer.
    Radiology, 243(1): 122-31. [Abstract] [Full-text]
85. Extramural depth of tumor invasion at thin-section MR in patients with rectal cancer: results of the MERCURY study.
    Radiology, 243(1): 132-9. [Abstract] [Full-text]
86. Decreased expression of insulin-like growth factor binding protein 7 in human colorectal carcinoma is related to DNA methylation.
    J Cancer Res Clin Oncol, 133(5): 305-14. [Abstract] [Full-text]
87. Absence of tyrosine kinase mutations in Japanese colorectal cancer patients.
    Oncogene, 26(14): 2133-5. [Abstract] [Full-text]
88. Molecular and immunological evaluation of the expression of cancer/testis gene products in human colorectal cancer.
    Cancer Immunol Immunother, 56(6): 839-47. [Abstract] [Full-text]
89. A randomised phase II study of irinotecan in combination with 5-FU/FA compared with irinotecan alone as second-line treatment of patients with metastatic colorectal carcinoma.
    Onkologie, 30(4): 169-74. [Abstract] [Full-text]
90. A newly devised scoring system for prediction of mortality in patients with colorectal cancer: a prospective study.
    Lancet Oncol, 8(4): 317-22. [Abstract] [Full-text]
91. Risk of anogenital cancer after diagnosis of cervical intraepithelial neoplasia: a prospective population-based study.
    Lancet Oncol, 8(4): 311-6. [Abstract] [Full-text]
92. A multivariate analysis of limiting factors for stoma reversal in patients with rectal cancer entered into the total mesorectal excision (TME) trial: a retrospective study.
    Lancet Oncol, 8(4): 297-303. [Abstract] [Full-text]
93. Phase I trial of preoperative hypofractionated intensity-modulated radiotherapy with incorporated boost and oral capecitabine in locally advanced rectal cancer.
    Int J Radiat Oncol Biol Phys, 67(5): 1389-93. [Abstract] [Full-text]
94. Colorectal neoplasia in Crohn's colitis: a retrospective comparative study with ulcerative colitis.
    Histopathology, 50(5): 574-83. [Abstract] [Full-text]
95. Conformal therapy improves the therapeutic index of patients with anal canal cancer treated with combined chemotherapy and external beam radiotherapy.
    Int J Radiat Oncol Biol Phys, 67(5): 1394-400. [Abstract] [Full-text]
96. Patterns of failure and local control after intraoperative electron boost radiotherapy to the presacral space in combination with total mesorectal excision in patients with locally advanced rectal cancer.
    Int J Radiat Oncol Biol Phys, 67(5): 1381-8. [Abstract] [Full-text]
97. Microsatellite instability in aberrant crypt foci from patients without concurrent colon cancer.
    Carcinogenesis, 28(4): 769-76. [Abstract] [Full-text]
98. Role of NQO1C609T and EPHX1 gene polymorphisms in the association of smoking and alcohol with sporadic distal colorectal adenomas: results from the UKFSS Study.
    Carcinogenesis, 28(4): 875-82. [Abstract] [Full-text]
99. Glutathione S-transferase phenotypes in relation to genetic variation and fruit and vegetable consumption in an endoscopy-based population.
    Carcinogenesis, 28(4): 848-57. [Abstract] [Full-text]

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