Colorectal Cancer Research Today is a free monthly online journal that collates and summarizes the latest research about Colorectal Cancer, including details on symptoms, genetics, screening, treatment, information.

Volume 4 (2007), Issue 2 (February)

1. Targeting inhibition of K-ras enhances Ad.mda-7-induced growth suppression and apoptosis in mutant K-ras colorectal cancer cells.
   Oncogene, 26(5): 733-44. [Abstract] [Full-text]
2. Depletion of CD4+CD25+ regulatory T cells enhances interleukin-2-induced antitumor immunity in a mouse model of colon adenocarcinoma.
   Cancer Sci, 98(3): 416-23. [Abstract] [Full-text]
3. Proto-oncogene, Pim-3 with serine/threonine kinase activity, is aberrantly expressed in human colon cancer cells and can prevent Bad-mediated apoptosis.
   Cancer Sci, 98(3): 321-8. [Abstract] [Full-text]
4. Specific overexpression of OLFM4(GW112/HGC-1) mRNA in colon, breast and lung cancer tissues detected using quantitative analysis.
   Cancer Sci, 98(3): 315-20. [Abstract] [Full-text]
5. Down-regulation of sialidase NEU4 may contribute to invasive properties of human colon cancers.
   Cancer Sci, 98(3): 299-307. [Abstract] [Full-text]
6. A new EGFR inhibitor induces apoptosis in colon cancer cells.
   Biochem Biophys Res Commun, 354(2): 409-13. [Abstract] [Full-text]
7. Coffee consumption and the risk of colorectal cancer: a prospective cohort study in Japan.
   Int J Cancer, 120(7): 1542-7. [Abstract] [Full-text]
8. Mismatch repair polymorphisms and the risk of colorectal cancer.
   Int J Cancer, 120(7): 1548-54. [Abstract] [Full-text]
9. Alterations in cell proliferation and apoptosis in colon cancers with microsatellite instability.
   Int J Cancer, 120(6): 1232-8. [Abstract] [Full-text]
10. Urinary biomarkers of tea polyphenols and risk of colorectal cancer in the Shanghai Cohort Study.
    Int J Cancer, 120(6): 1344-50. [Abstract] [Full-text]
11. 99mTc(CO)3-VIP analogues: preparation and evaluation as tumor imaging agent.
    Appl Radiat Isot, 65(4): 382-6. [Abstract] [Full-text]
12. Genetic variation in base excision repair genes and the prevalence of advanced colorectal adenoma.
    Cancer Res, 67(3): 1395-404. [Abstract] [Full-text]
13. Targeted and nontargeted effects of low-dose ionizing radiation on delayed genomic instability in human cells.
    Cancer Res, 67(3): 1099-104. [Abstract] [Full-text]
14. Colon cancer cell-derived tumor necrosis factor-alpha mediates the tumor growth-promoting response in macrophages by up-regulating the colony-stimulating factor-1 pathway.
    Cancer Res, 67(3): 1038-45. [Abstract] [Full-text]
15. Hematopoietic prostaglandin D synthase suppresses intestinal adenomas in ApcMin/+ mice.
    Cancer Res, 67(3): 881-9. [Abstract] [Full-text]
16. GSTT2 promoter polymorphisms and colorectal cancer risk.
    BMC Cancer, 7: 16. [Abstract] [Full-text]
17. Performance of different microsatellite marker panels for detection of mismatch repair-deficient colorectal tumors.
    J Natl Cancer Inst, 99(3): 244-52. [Abstract] [Full-text]
18. Magnesium intake and colorectal cancer risk in the Netherlands Cohort Study.
    Br J Cancer, 96(3): 510-3. [Abstract] [Full-text]
19. Uracil/ftorafur/leucovorin combined with irinotecan (TEGAFIRI) or oxaliplatin (TEGAFOX) as first-line treatment for metastatic colorectal cancer patients: results of randomised phase II study.
    Br J Cancer, 96(3): 439-44. [Abstract] [Full-text]
20. Brain tumors in individuals with familial adenomatous polyposis: a cancer registry experience and pooled case report analysis.
    Cancer, 109(4): 761-6. [Abstract] [Full-text]
21. Survival after hepatic resection in metastatic colorectal cancer: a population-based study.
    Cancer, 109(4): 718-26. [Abstract] [Full-text]
22. Use of adjuvant radiotherapy at hospitals with and without on-site radiation services.
    Cancer, 109(4): 796-801. [Abstract] [Full-text]
23. Differential effects of endoplasmic reticulum stress-induced autophagy on cell survival.
    J Biol Chem, 282(7): 4702-10. [Abstract] [Full-text]
24. Enhanced estrogenic responses and sensitivity to azoxymethane following dietary soy isoflavone supplementation in older female rats.
    Food Chem Toxicol, 45(4): 628-37. [Abstract] [Full-text]
25. Disparities in colon cancer screening in the Medicare population.
    Arch Intern Med, 167(3): 258-64. [Abstract] [Full-text]
26. Cigarette smoking and the risk of colorectal cancer among men: a prospective study in Japan.
    Eur J Cancer Prev, 16(2): 102-7. [Abstract] [Full-text]
27. Inheritance of a cancer-associated MLH1 germ-line epimutation.
    N Engl J Med, 356(7): 697-705. [Abstract] [Full-text]
28. A positive feedback loop between hepatocyte growth factor receptor and beta-catenin sustains colorectal cancer cell invasive growth.
    Oncogene, 26(7): 1078-87. [Abstract] [Full-text]
29. Bombesin induces cyclooxygenase-2 expression through the activation of the nuclear factor of activated T cells and enhances cell migration in Caco-2 colon carcinoma cells.
    Oncogene, 26(7): 958-69. [Abstract] [Full-text]
30. The new paradigm in the treatment of colorectal cancer: are we hitting the right target?
    Expert Opin Investig Drugs, 16(3): 311-24. [Abstract] [Full-text]
31. Quality of life outcomes in 599 cancer and non-cancer patients with colostomies.
    J Surg Res, 138(1): 79-87. [Abstract] [Full-text]
32. Combining siRNAs at two different sites in the EGFR to suppress its expression, induce apoptosis, and enhance 5-fluorouracil sensitivity of colon cancer cells.
    J Surg Res, 138(1): 56-63. [Abstract] [Full-text]
33. p38-mediated inactivation of cyclin D1/cyclin-dependent kinase 4 stimulates nucleolar translocation of RelA and apoptosis in colorectal cancer cells.
    Cancer Res, 67(4): 1660-9. [Abstract] [Full-text]
34. Smad4 regulates claudin-1 expression in a transforming growth factor-beta-independent manner in colon cancer cells.
    Cancer Res, 67(4): 1571-9. [Abstract] [Full-text]
35. Genetic unmasking of an epigenetically silenced microRNA in human cancer cells.
    Cancer Res, 67(4): 1424-9. [Abstract] [Full-text]
36. Sensitivity of the hazard ratio to nonignorable treatment assignment in an observational study.
    Stat Med, 26(6): 1398-414. [Abstract] [Full-text]
37. Chronomodulated administration of oxaliplatin plus capecitabine (XELOX) as first line chemotherapy in advanced colorectal cancer patients: phase II study.
    Cancer Chemother Pharmacol, 59(5): 613-20. [Abstract] [Full-text]
38. Antitumor activity of HER1/EGFR tyrosine kinase inhibitor erlotinib, alone and in combination with CPT-11 (irinotecan) in human colorectal cancer xenograft models.
    Cancer Chemother Pharmacol, 59(5): 651-9. [Abstract] [Full-text]
39. A weighted logistic regression model for estimation of recurrence of adenomas.
    Stat Med, 26(7): 1567-78. [Abstract] [Full-text]
40. Adherence and anticarcinogenic effects of Bacillus polyfermenticus SCD in the large intestine.
    Lett Appl Microbiol, 44(3): 274-8. [Abstract] [Full-text]
41. Lynch syndrome (hereditary nonpolyposis colorectal cancer) diagnostics.
    J Natl Cancer Inst, 99(4): 291-9. [Abstract] [Full-text]
42. Alcohol consumption and distinct molecular pathways to colorectal cancer.
    Br J Nutr, 97(3): 430-4. [Abstract] [Full-text]
43. Dosimetric study and in-vivo dose verification for conformal avoidance treatment of anal adenocarcinoma using helical tomotherapy.
    Med Dosim, 32(1): 33-7. [Abstract] [Full-text]
44. Microsatellite-unstable mucinous colorectal carcinoma occurring in the elderly: comparison with medullary type poorly differentiated adenocarcinoma.
    Pathol Int, 57(4): 205-12. [Abstract] [Full-text]
45. Overexpression of serine-threonine receptor kinase-associated protein in colorectal cancers.
    Pathol Int, 57(4): 178-82. [Abstract] [Full-text]
46. The role of surgical intervention in non-Hodgkin's lymphoma of the colon and rectum.
    Am J Surg, 193(3): 409-12; discussion 412. [Abstract] [Full-text]
47. Preoperative chemoradiation for rectal cancer: results of multimodality management and analysis of prognostic factors.
    Am J Surg, 193(3): 389-93; discussion 393-4. [Abstract] [Full-text]
48. A pilot study to assess the safety and efficacy of carbon dioxide insufflation during colorectal endoscopic submucosal dissection with the patient under conscious sedation.
    Gastrointest Endosc, 65(3): 537-42. [Abstract] [Full-text]
49. Herbal diterpenoids induce growth arrest and apoptosis in colon cancer cells with increased expression of the nonsteroidal anti-inflammatory drug-activated gene.
    Eur J Pharmacol, 559(1): 1-13. [Abstract] [Full-text]
50. Quantitative tumor perfusion assessment with multidetector CT: are measurements from two commercial software packages interchangeable?
    Radiology, 242(3): 777-82. [Abstract] [Full-text]
51. Tomographic fluorescence imaging of tumor vascular volume in mice.
    Radiology, 242(3): 751-8. [Abstract] [Full-text]
52. What do gay men know about human papillomavirus? Australian gay men's knowledge and experience of anal cancer screening and human papillomavirus.
    Sex Transm Dis, 34(3): 170-3. [Abstract] [Full-text]
53. Gene expression signature in advanced colorectal cancer patients select drugs and response for the use of leucovorin, fluorouracil, and irinotecan.
    J Clin Oncol, 25(7): 773-80. [Abstract] [Full-text]
54. Prognostic and predictive roles of high-degree microsatellite instability in colon cancer: a National Cancer Institute-National Surgical Adjuvant Breast and Bowel Project Collaborative Study.
    J Clin Oncol, 25(7): 767-72. [Abstract] [Full-text]
55. Clinicopathologic and pedigree differences in amsterdam I-positive hereditary nonpolyposis colorectal cancer families according to tumor microsatellite instability status.
    J Clin Oncol, 25(7): 781-6. [Abstract] [Full-text]
56. Chemotherapy-associated hepatotoxicity and surgery for colorectal liver metastases.
    Br J Surg, 94(3): 274-86. [Abstract] [Full-text]
57. Oncological outcome of ultra-low coloanal anastomosis with and without intersphincteric resection for low rectal adenocarcinoma.
    Br J Surg, 94(3): 341-5. [Abstract] [Full-text]
58. Frequency and impact of extracolonic findings detected at computed tomographic colonography in a symptomatic population.
    Br J Surg, 94(3): 355-61. [Abstract] [Full-text]
59. Colitis and colitis-associated cancer are exacerbated in mice deficient for tumor protein 53-induced nuclear protein 1.
    Mol Cell Biol, 27(6): 2215-28. [Abstract] [Full-text]
60. Carbonic anhydrase-related protein VIII promotes colon cancer cell growth.
    Mol Carcinog, 46(3): 208-14. [Abstract] [Full-text]
61. Leptin acts as a mitogenic and antiapoptotic factor for colonic cancer cells.
    Br J Surg, 94(3): 346-54. [Abstract] [Full-text]
62. Differential apoptosis by gallotannin in human colon cancer cells with distinct p53 status.
    Mol Carcinog, 46(3): 176-86. [Abstract] [Full-text]
63. Pinocembrin triggers Bax-dependent mitochondrial apoptosis in colon cancer cells.
    Mol Carcinog, 46(3): 231-41. [Abstract] [Full-text]
64. Laparoscopic surgery impairs tissue oxygen tension more than open surgery.
    Br J Surg, 94(3): 362-8. [Abstract] [Full-text]
65. Matrix metalloproteinase-7-catalyzed release of HB-EGF mediates deoxycholyltaurine-induced proliferation of a human colon cancer cell line.
    Biochem Pharmacol, 73(7): 1001-12. [Abstract] [Full-text]

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