Colorectal Cancer Research - Symptoms, Genetics, Screening, Treatment, Information

Colorectal Cancer Research Today is a free monthly online journal that collates and summarizes the latest research about Colorectal Cancer, including details on symptoms, genetics, screening, treatment, information.


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Volume 3 (2006), Issue 3 (March)

  1. Ectopic expression of neutrophil gelatinase-associated lipocalin suppresses the invasion and liver metastasis of colon cancer cells.
    Int J Cancer, 118(10): 2490-7. [Abstract] [Full-text]
  2. Influence of target gene mutations on survival, stage and histology in sporadic microsatellite unstable colon cancers.
    Int J Cancer, 118(10): 2509-13. [Abstract] [Full-text]
  3. Enhancing effects of simultaneous treatment with sodium nitrite on 2-amino-3-methylimidazo[4,5-f]quinoline-induced rat liver, colon and Zymbal's gland carcinogenesis after initiation with diethylnitrosamine and 1,2-dimethylhydrazine.
    Int J Cancer, 118(10): 2399-404. [Abstract] [Full-text]
  4. Celecoxib induces anoikis in human colon carcinoma cells associated with the deregulation of focal adhesions and nuclear translocation of p130Cas.
    Int J Cancer, 118(10): 2381-9. [Abstract] [Full-text]
  5. Age of diagnosis of colorectal cancer in HNPCC patients is more complex than that predicted by R72P polymorphism in TP53.
    Int J Cancer, 118(10): 2479-84. [Abstract] [Full-text]
  6. Self-surveillance for genetic predisposition to cancer: behaviors and emotions.
    Oncol Nurs Forum, 33(2): 221-31. [Abstract] [Full-text]
  7. Peroxisome-proliferator-activated receptor alpha agonists inhibit cyclo-oxygenase 2 and vascular endothelial growth factor transcriptional activation in human colorectal carcinoma cells via inhibition of activator protein-1.
    Biochem J, 395(1): 81-8. [Abstract] [Full-text]
  8. All-trans retinoic acid induces XAF1 expression through an interferon regulatory factor-1 element in colon cancer.
    Gastroenterology, 130(3): 747-58. [Abstract] [Full-text]
  9. Decrease in mortality in Lynch syndrome families because of surveillance.
    Gastroenterology, 130(3): 665-71. [Abstract] [Full-text]
  10. Colon cancer and apoptosis.
    Am J Surg, 191(4): 517-26. [Abstract] [Full-text]
  11. Primary tumour genetic alterations and intra-tumoral heterogeneity are maintained in xenografts of human colon cancers showing chromosome instability.
    J Pathol, 208(5): 643-52. [Abstract] [Full-text]
  12. A new approach to the validation of tissue microarrays.
    J Pathol, 208(5): 607-14. [Abstract] [Full-text]
  13. p53 is involved in clearance of ionizing radiation-induced RAD51 foci in a human colon cancer cell line.
    Biochem Biophys Res Commun, 342(4): 1211-7. [Abstract] [Full-text]
  14. Hyperinsulinemia, but not other factors associated with insulin resistance, acutely enhances colorectal epithelial proliferation in vivo.
    Endocrinology, 147(4): 1830-7. [Abstract] [Full-text]
  15. CpG oligonucleotides enhance the tumor antigen-specific immune response of an anti-idiotype antibody-based vaccine strategy in CEA transgenic mice.
    Cancer Immunol Immunother, 55(5): 515-27. [Abstract] [Full-text]
  16. Differential CD146 expression on circulating versus tissue endothelial cells in rectal cancer patients: implications for circulating endothelial and progenitor cells as biomarkers for antiangiogenic therapy.
    J Clin Oncol, 24(9): 1449-53. [Abstract] [Full-text]
  17. Hepatic arterial infusion versus systemic therapy for hepatic metastases from colorectal cancer: a randomized trial of efficacy, quality of life, and molecular markers (CALGB 9481).
    J Clin Oncol, 24(9): 1395-403. [Abstract] [Full-text]
  18. Immunohistochemical prognostic factors in resected colorectal lung metastases using tissue microarray analysis.
    Eur J Surg Oncol, 32(3): 308-9. [Abstract] [Full-text]
  19. Pre-operative combined modality therapy in the management of locally advanced rectal cancer.
    Eur J Surg Oncol, 32(3): 259-68. [Abstract] [Full-text]
  20. Extended right-sided liver resection for colorectal liver metastases--impact of percutaneous portal venous embolisation.
    Eur J Surg Oncol, 32(3): 292-6. [Abstract] [Full-text]
  21. Prognostic relevance of occult tumour cells in lymph nodes in colorectal cancer.
    Eur J Surg Oncol, 32(3): 253-8. [Abstract] [Full-text]
  22. Sentinel lymph node in carcinoma of the anal canal: a review.
    Eur J Surg Oncol, 32(3): 247-52. [Abstract] [Full-text]
  23. Immunotherapy with dendritic cells and CpG oligonucleotides can be combined with chemotherapy without loss of efficacy in a mouse model of colon cancer.
    Int J Cancer, 118(11): 2790-5. [Abstract] [Full-text]
  24. Prevention of colitis-associated carcinogenesis in a mouse model by diet supplementation with ursodeoxycholic acid.
    Int J Cancer, 118(11): 2750-7. [Abstract] [Full-text]
  25. TAK1-mediated stress signaling pathways are essential for TNF-alpha-promoted pulmonary metastasis of murine colon cancer cells.
    Int J Cancer, 118(11): 2758-64. [Abstract] [Full-text]
  26. BRAF mutation, CpG island methylator phenotype and microsatellite instability occur more frequently and concordantly in mucinous than non-mucinous colorectal cancer.
    Int J Cancer, 118(11): 2765-71. [Abstract] [Full-text]
  27. The Wnt antagonist sFRP1 is downregulated in premalignant large bowel adenomas.
    Br J Cancer, 94(6): 922-7. [Abstract] [Full-text]
  28. FOLFOXIRI (folinic acid, 5-fluorouracil, oxaliplatin and irinotecan) vs FOLFIRI (folinic acid, 5-fluorouracil and irinotecan) as first-line treatment in metastatic colorectal cancer (MCC): a multicentre randomised phase III trial from the Hellenic Oncology Research Group (HORG).
    Br J Cancer, 94(6): 798-805. [Abstract] [Full-text]
  29. Cetuximab and irinotecan as third-line therapy in advanced colorectal cancer patients: a single centre phase II trial.
    Br J Cancer, 94(6): 792-7. [Abstract] [Full-text]
  30. Cyclin D1 A870G polymorphism and the risk of colorectal cancer and adenoma.
    Br J Cancer, 94(6): 928-34. [Abstract] [Full-text]
  31. Coffee consumption and incidence of colorectal cancer in two prospective cohort studies of Swedish women and men.
    Am J Epidemiol, 163(7): 638-44. [Abstract] [Full-text]
  32. Neurotensin receptor 1 gene activation by the Tcf/beta-catenin pathway is an early event in human colonic adenomas.
    Carcinogenesis, 27(4): 708-16. [Abstract] [Full-text]
  33. NO-donating aspirin induces phase II enzymes in vitro and in vivo.
    Carcinogenesis, 27(4): 803-10. [Abstract] [Full-text]
  34. The outcome after restorative proctocolectomy with or without defunctioning ileostomy.
    Dis Colon Rectum, 49(4): 470-7. [Abstract] [Full-text]
  35. Imaging techniques contribute to increased surgical rescue of relapse in the follow-up of colorectal cancer.
    Dis Colon Rectum, 49(4): 478-84. [Abstract] [Full-text]
  36. Preoperative oral immune-enhancing nutritional supplementation corrects TH1/TH2 imbalance in patients undergoing elective surgery for colorectal cancer.
    Dis Colon Rectum, 49(4): 507-16. [Abstract] [Full-text]
  37. Experimental study of the survival of metastatic cancer cells in corneal organ culture.
    Invest Ophthalmol Vis Sci, 47(4): 1339-47. [Abstract] [Full-text]
  38. Loss of Ku70/Ku80 expression occurs more frequently in hereditary than in sporadic colorectal tumors. Tissue microarray study.
    Hum Pathol, 37(4): 448-52. [Abstract] [Full-text]
  39. A phase II study of radiofrequency ablation of unresectable metastatic colorectal cancer with hepatic arterial infusion pump chemotherapy.
    J Surg Oncol, 93(5): 387-93. [Abstract] [Full-text]
  40. Is surgery-only the adequate treatment approach for T2N0 rectal cancer?
    J Surg Oncol, 93(5): 350-4. [Abstract] [Full-text]
  41. Down-regulation of BCRP/ABCG2 in colorectal and cervical cancer.
    Biochem Biophys Res Commun, 343(2): 571-7. [Abstract] [Full-text]
  42. Desferrioxamine, an iron chelator, enhances HIF-1alpha accumulation via cyclooxygenase-2 signaling pathway.
    Biochem Biophys Res Commun, 343(1): 8-14. [Abstract] [Full-text]
  43. Associations between the age at diagnosis and location of colorectal cancer and the use of alcohol and tobacco: implications for screening.
    Arch Intern Med, 166(6): 629-34. [Abstract] [Full-text]
  44. N-myristoyltransferase 2 expression in human colon cancer: cross-talk between the calpain and caspase system.
    FEBS Lett, 580(8): 2021-6. [Abstract] [Full-text]
  45. Overexpression in colorectal carcinoma of two lysosomal enzymes, CLN2 and CLN1, involved in neuronal ceroid lipofuscinosis.
    Cancer, 106(7): 1489-97. [Abstract] [Full-text]
  46. The impact of blood loss, obstruction and perforation on survival in patients undergoing curative resection for colon cancer.
    Br J Surg, 93(4): 483-8. [Abstract] [Full-text]
  47. Microsatellite instability in colorectal cancer.
    Br J Surg, 93(4): 395-406. [Abstract] [Full-text]
  48. Repeat hepatic resection for recurrent colorectal liver metastases is associated with favourable long-term survival.
    Br J Surg, 93(4): 457-64. [Abstract] [Full-text]
  49. A population-based study of the incidence, management and prognosis of hepatic metastases from colorectal cancer.
    Br J Surg, 93(4): 465-74. [Abstract] [Full-text]
  50. Meta-analysis of observational studies of ileorectal versus ileal pouch-anal anastomosis for familial adenomatous polyposis.
    Br J Surg, 93(4): 407-17. [Abstract] [Full-text]
  51. Population-based study of risk factors for postoperative death after anterior resection of the rectum.
    Br J Surg, 93(4): 498-503. [Abstract] [Full-text]
  52. Tumor thymidylate synthase 1494del6 genotype as a prognostic factor in colorectal cancer patients receiving fluorouracil-based adjuvant treatment.
    J Clin Oncol, 24(10): 1603-11. [Abstract] [Full-text]
  53. Use of antidepressants and risk of colorectal cancer: a nested case-control study.
    Lancet Oncol, 7(4): 301-8. [Abstract] [Full-text]
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Colorectal Cancer Research Today Archive:

Volume 1 (2004)
  Issue 1 (August)
  Issue 2 (September)
  Issue 3 (October)
  Issue 4 (November)
  Issue 5 (December)

Volume 2 (2005)
  Issue 1 (January)
  Issue 2 (February)
  Issue 3 (March)
  Issue 4 (April)
  Issue 5 (May)
  Issue 6 (June)
  Issue 7 (July)
  Issue 8 (August)
  Issue 9 (September)
  Issue 10 (October)
  Issue 11 (November)
  Issue 12 (December)

Volume 3 (2006)
  Issue 1 (January)
  Issue 2 (February)
  Issue 3 (March)
  Issue 4 (April)
  Issue 5 (May)
  Issue 6 (June)
  Issue 7 (July)
  Issue 8 (August)
  Issue 9 (September)
  Issue 10 (October)
  Issue 11 (November)
  Issue 12 (December)

Volume 4 (2007)
  Issue 1 (January)
  Issue 2 (February)
  Issue 3 (March)
  Issue 4 (April)
  Issue 5 (May)
  Issue 6 (June)
  Issue 7 (July)
  Issue 8 (August)
  Issue 9 (September)
  Issue 10 (October)
  Issue 11 (November)
  Issue 12 (December)

Volume 5 (2008)
  Issue 1 (January)
  Issue 2 (February)
  Issue 3 (March)
  Issue 4 (April)
  Issue 5 (May)
  Issue 6 (June)
  Issue 7 (July)
  Issue 8 (August)



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