Colorectal Cancer Research - Symptoms, Genetics, Screening, Treatment, Information

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Volume 2 (2005), Issue 8 (August)

  1. Arg462Gln sequence variation in the prostate-cancer-susceptibility gene RNASEL and age of onset of hereditary non-polyposis colorectal cancer: a case-control study.
    Lancet Oncol, 6(8): 566-72. [Abstract] [Full-text]
  2. Deregulated GSK3beta activity in colorectal cancer: its association with tumor cell survival and proliferation.
    Biochem Biophys Res Commun, 334(4): 1365-73. [Abstract] [Full-text]
  3. Randomized clinical trial of the anabolic effect of hypocaloric parenteral nutrition after abdominal surgery.
    Br J Surg, 92(8): 947-53. [Abstract] [Full-text]
  4. Cancer surveillance in ulcerative colitis.
    Br J Surg, 92(8): 928-36. [Abstract] [Full-text]
  5. Combination of cyclooxygenase-2 inhibitors and oxaliplatin increases the growth inhibition and death in human colon cancer cells.
    Biochem Pharmacol, 70(5): 658-67. [Abstract] [Full-text]
  6. Generation of a unique strain of multiple intestinal neoplasia (Apc(+/Min-FCCC)) mice with significantly increased numbers of colorectal adenomas.
    Mol Carcinog, 44(1): 31-41. [Abstract] [Full-text]
  7. Clinical significance of Ki-67 proliferation index in disease progression and prognosis of patients with resected colorectal carcinoma.
    Br J Surg, 92(8): 1002-7. [Abstract] [Full-text]
  8. Improvement in survival following surgery for colorectal cancer.
    Br J Surg, 92(8): 1008-13. [Abstract] [Full-text]
  9. Epoxide hydrolase and CYP2C9 polymorphisms, cigarette smoking, and risk of colorectal carcinoma in the Nurses' Health Study and the Physicians' Health Study.
    Mol Carcinog, 44(1): 21-30. [Abstract] [Full-text]
  10. RAD001 (everolimus) improves the efficacy of replicating adenoviruses that target colon cancer.
    Cancer Res, 65(15): 6882-90. [Abstract] [Full-text]
  11. Differential nonsense mediated decay of mutated mRNAs in mismatch repair deficient colorectal cancers.
    Hum Mol Genet, 14(16): 2435-42. [Abstract] [Full-text]
  12. In vitro antiproliferative activity against human colon cancer cell lines of representative 4-thiazolidinones. Part I.
    Bioorg Med Chem Lett, 15(17): 3930-3. [Abstract] [Full-text]
  13. Dietary supplement of isohumulones inhibits the formation of aberrant crypt foci with a concomitant decrease in prostaglandin E2 level in rat colon.
    Mol Nutr Food Res, 49(8): 772-8. [Abstract] [Full-text]
  14. Inhibition of colon cancer cell proliferation by the dietary compound conjugated linoleic acid is mediated by the CDK inhibitor p21CIP1/WAF1.
    J Cell Physiol, 205(1): 107-13. [Abstract] [Full-text]
  15. Detection in fecal DNA of colon cancer-specific methylation of the nonexpressed vimentin gene.
    J Natl Cancer Inst, 97(15): 1124-32. [Abstract] [Full-text]
  16. Capecitabine as third line therapy in patients with advanced colorectal cancer.
    Acta Oncol, 44(3): 236-9. [Abstract] [Full-text]
  17. Multicenter phase II study of oral capecitabine plus irinotecan as first-line chemotherapy in advanced colorectal cancer: a Korean Cancer Study Group trial.
    Acta Oncol, 44(3): 230-5. [Abstract] [Full-text]
  18. High-dose radiotherapy and concurrent UFT plus l-leucovorin in locally advanced rectal cancer: a phase I trial.
    Acta Oncol, 44(3): 224-9. [Abstract] [Full-text]
  19. Lifestyle and 30-day complications to surgery for colorectal cancer.
    Acta Oncol, 44(3): 218-23. [Abstract] [Full-text]
  20. Targeted drugs in metastatic colorectal cancer with special emphasis on guidelines for the use of bevacizumab and cetuximab: an Acta Oncologica expert report.
    Acta Oncol, 44(3): 203-17. [Abstract] [Full-text]
  21. Clinicopathological features and microsatellite instability (MSI) in colorectal cancers from African Americans.
    Int J Cancer, 116(6): 914-9. [Abstract] [Full-text]
  22. Selective infiltration of CCR5(+)CXCR3(+) T lymphocytes in human colorectal carcinoma.
    Int J Cancer, 116(6): 949-56. [Abstract] [Full-text]
  23. Sulindac corrects defective apoptosis and suppresses azoxymethane-induced colonic oncogenesis in p53 knockout mice.
    Int J Cancer, 116(6): 870-5. [Abstract] [Full-text]
  24. Expression of D-type cyclins in colon cancer and in cell lines from colon carcinomas.
    Br J Cancer, 93(3): 338-45. [Abstract] [Full-text]
  25. Accumulation of mitochondrial DNA mutation with colorectal carcinogenesis in ulcerative colitis.
    Br J Cancer, 93(3): 331-7. [Abstract] [Full-text]
  26. Trefoil factor family-3 is associated with aggressive behavior of colon cancer cells.
    Clin Exp Metastasis, 22(2): 157-65. [Abstract] [Full-text]
  27. Effects of agmatine accumulation in human colon carcinoma cells on polyamine metabolism, DNA synthesis and the cell cycle.
    Biochim Biophys Acta, 1745(1): 111-23. [Abstract] [Full-text]
  28. Correlation of AIB1 overexpression with advanced clinical stage of human colorectal carcinoma.
    Hum Pathol, 36(7): 777-83. [Abstract] [Full-text]
  29. Functional significance and clinical phenotype of nontruncating mismatch repair variants of MLH1.
    Gastroenterology, 129(2): 537-49. [Abstract] [Full-text]
  30. Insulin-like growth factor-I and insulin are associated with the presence and advancement of adenomatous polyps.
    Gastroenterology, 129(2): 464-75. [Abstract] [Full-text]
  31. A comparison of the immunochemical fecal occult blood test and total colonoscopy in the asymptomatic population.
    Gastroenterology, 129(2): 422-8. [Abstract] [Full-text]
  32. Cancer risk in hereditary nonpolyposis colorectal cancer syndrome: later age of onset.
    Gastroenterology, 129(2): 415-21. [Abstract] [Full-text]
  33. Clinical and genetic findings in an Ashkenazi Jewish population with colorectal neoplasms.
    Cancer, 104(4): 719-29. [Abstract] [Full-text]
  34. Molecular characterization of the spectrum of genomic deletions in the mismatch repair genes MSH2, MLH1, MSH6, and PMS2 responsible for hereditary nonpolyposis colorectal cancer (HNPCC).
    Genes Chromosomes Cancer, 44(2): 123-38. [Abstract] [Full-text]
  35. Dietary calcium, phosphorus, vitamin D, dairy products and the risk of colorectal adenoma and cancer among French women of the E3N-EPIC prospective study.
    Int J Cancer, 117(1): 137-44. [Abstract] [Full-text]
  36. Potential anti-cancer effects of virgin olive oil phenols on colorectal carcinogenesis models in vitro.
    Int J Cancer, 117(1): 1-7. [Abstract] [Full-text]
  37. Cholecystectomy and the risk of colorectal cancer.
    Am J Gastroenterol, 100(8): 1813-20. [Abstract] [Full-text]
  38. Colorectal cancer screening in HIV-infected patients 50 years of age and older: missed opportunities for prevention.
    Am J Gastroenterol, 100(8): 1805-12. [Abstract] [Full-text]
  39. Diclofenac attenuates Wnt/beta-catenin signaling in colon cancer cells by activation of NF-kappaB.
    FEBS Lett, 579(20): 4213-8. [Abstract] [Full-text]
  40. Dendritic cells and vascular endothelial growth factor in colorectal cancer: correlations with clinicobiological findings.
    Oncology, 68(2): 276-84. [Abstract] [Full-text]
  41. Plasma gelatinase activity does not reflect disease activity after operation for colorectal cancer.
    Oncology, 68(2): 256-62. [Abstract] [Full-text]
  42. Prognostic and predictive relevance of DNAM-1, SOCS6 and CADH-7 genes on chromosome 18q in colorectal cancer.
    Oncology, 68(2): 246-55. [Abstract] [Full-text]
  43. Clinical significance of nuclear morphometry at the invasive front of T1 colorectal cancer and relation to expression of VEGF-A and VEGF-C.
    Oncology, 68(2): 230-8. [Abstract] [Full-text]
  44. Alterations in connexin26 expression during colorectal carcinogenesis.
    Oncology, 68(2): 217-22. [Abstract] [Full-text]
  45. The role of 5-fluorouracil (5-FU) reintroduction with irinotecan or oxaliplatin in truly 5-FU-refractory advanced colorectal cancer patients.
    Oncology, 68(2): 212-6. [Abstract] [Full-text]
  46. Autocrine vascular endothelial growth factor/vascular endothelial growth factor receptor-2 growth pathway represents a cyclooxygenase-2-independent target for the cyclooxygenase-2 inhibitor NS-398 in colon cancer cells.
    Oncology, 68(2): 204-11. [Abstract] [Full-text]
  47. Dendritic cells transduced with tumor-associated antigen gene elicit potent therapeutic antitumor immunity: comparison with immunodominant peptide-pulsed DCs.
    Oncology, 68(2): 163-70. [Abstract] [Full-text]
  48. Interleukin-1 receptor antagonist inhibits the expression of vascular endothelial growth factor in colorectal carcinoma.
    Oncology, 68(2): 138-45. [Abstract] [Full-text]
  49. Collision/composite tumors of the adrenal gland: a pitfall of scintigraphy imaging and hormone assays in the detection of adrenal metastasis.
    J Clin Endocrinol Metab, 90(8): 4924-9. [Abstract] [Full-text]
  50. Characteristics of apoptosis in HCT116 colon cancer cells induced by deoxycholic acid.
    J Biochem (Tokyo), 138(2): 151-7. [Abstract] [Full-text]
  51. Web-based data warehouse on gene expression in human colorectal cancer.
    Proteomics, 5(12): 3066-78. [Abstract] [Full-text]
  52. Targeting signal transduction pathways in colorectal cancer--more than skin deep.
    J Clin Oncol, 23(23): 5374-85. [Abstract] [Full-text]
  53. Increase in autoantibodies against Fas (CD95) during carcinogenesis in the human colon: a hope for the immunoprevention of cancer?
    Cancer Immunol Immunother, 54(10): 1038-42. [Abstract] [Full-text]
  54. Colorectal cancer: mutations in a signalling pathway.
    Nature, 436(7052): 792. [Abstract] [Full-text]
  55. An exploratory comparison of genetic counselling protocols for HNPCC predictive testing.
    Clin Genet, 68(3): 255-61. [Abstract] [Full-text]
  56. Novel genomic insertion-- deletion in MLH1: possible mechanistic role for non-homologous end-joining DNA repair.
    Clin Genet, 68(3): 234-8. [Abstract] [Full-text]
  57. Pharmacokinetic profile of cetuximab (Erbitux) alone and in combination with irinotecan in patients with advanced EGFR-positive adenocarcinoma.
    Eur J Cancer, 41(12): 1739-45. [Abstract] [Full-text]
  58. Up regulation of ICAM-1 gene expression inhibits tumour growth and liver metastasis in colorectal carcinoma.
    Eur J Cancer, 41(12): 1802-10. [Abstract] [Full-text]
  59. Influence of P-glycoprotein expression on in vitro cytotoxicity and in vivo antitumour activity of the novel pyrrolobenzodiazepine dimer SJG-136.
    Eur J Cancer, 41(12): 1811-8. [Abstract] [Full-text]
  60. Preoperative oral antibiotics in colorectal surgery increase the rate of Clostridium difficile colitis.
    Arch Surg, 140(8): 752-6. [Abstract] [Full-text]
  61. The evolving role of staging laparoscopy in the treatment of colorectal hepatic metastasis.
    Arch Surg, 140(8): 727-34. [Abstract] [Full-text]
  62. Live cell catapulting and recultivation does not change the karyotype of HCT116 tumor cells.
    Cancer Genet Cytogenet, 161(2): 174-7. [Abstract] [Full-text]
  63. Leptin is associated with an increased female colorectal cancer risk: a nested case-control study in Japan.
    Oncology, 68(4): 454-61. [Abstract] [Full-text]
  64. Serum lipid profile in colorectal cancer patients with and without synchronous distant metastases.
    Oncology, 68(4): 371-4. [Abstract] [Full-text]
  65. Prospective, double-blind, placebo-controlled, multicenter, randomized phase III study with orally administered budesonide for prevention of irinotecan (CPT-11)-induced diarrhea in patients with advanced colorectal cancer.
    Oncology, 68(4): 326-32. [Abstract] [Full-text]
  66. Epithelial syndecan-1 expression is associated with stage and grade in colorectal cancer.
    Oncology, 68(4): 306-13. [Abstract] [Full-text]
  67. Acid sphingomyelinase is induced by butyrate but does not initiate the anticancer effect of butyrate in HT29 and HepG2 cells.
    J Lipid Res, 46(9): 1944-52. [Abstract] [Full-text]
  68. The role of MLH1, MSH2 and MSH6 in the development of multiple colorectal cancers.
    Br J Cancer, 93(4): 472-7. [Abstract] [Full-text]
  69. Clinical features of colorectal cancer before diagnosis: a population-based case-control study.
    Br J Cancer, 93(4): 399-405. [Abstract] [Full-text]
  70. Explaining black-white differences in receipt of recommended colon cancer treatment.
    J Natl Cancer Inst, 97(16): 1211-20. [Abstract] [Full-text]
  71. Presentation, treatment, and multivariate analysis of risk factors for obstructive and perforative colorectal carcinoma.
    Am J Surg, 190(3): 376-82. [Abstract] [Full-text]
  72. Manganese superoxide dismutase induces p53-dependent senescence in colorectal cancer cells.
    Mol Cell Biol, 25(17): 7758-69. [Abstract] [Full-text]
  73. Adenomatous polyposis families that screen APC mutation-negative by conventional methods are genetically heterogeneous.
    J Clin Oncol, 23(24): 5651-9. [Abstract] [Full-text]
  74. Swedish Rectal Cancer Trial: long lasting benefits from radiotherapy on survival and local recurrence rate.
    J Clin Oncol, 23(24): 5644-50. [Abstract] [Full-text]
  75. Determination of TP53 mutation is more relevant than microsatellite instability status for the prediction of disease-free survival in adjuvant-treated stage III colon cancer patients.
    J Clin Oncol, 23(24): 5635-43. [Abstract] [Full-text]
  76. Phase II study of gefitinib, fluorouracil, leucovorin, and oxaliplatin therapy in previously treated patients with metastatic colorectal cancer.
    J Clin Oncol, 23(24): 5613-9. [Abstract] [Full-text]
  77. Enhanced tumorocidal effect of chemotherapy with preoperative radiotherapy for rectal cancer: preliminary results--EORTC 22921.
    J Clin Oncol, 23(24): 5620-7. [Abstract] [Full-text]
  78. Detection of thymidylate synthase expression in lymph node metastases of colorectal cancer can improve the prognostic information.
    J Clin Oncol, 23(24): 5628-34. [Abstract] [Full-text]
  79. Organ sparing by conformal avoidance intensity-modulated radiation therapy for anal cancer: dosimetric evaluation of coverage of pelvis and inguinal/femoral nodes.
    Int J Radiat Oncol Biol Phys, 63(1): 274-81. [Abstract] [Full-text]
  80. Proliferative signaling by store-operated calcium channels opposes colon cancer cell cytostasis induced by bacterial enterotoxins.
    J Pharmacol Exp Ther, 314(3): 1013-22. [Abstract] [Full-text]
  81. The influence of gender on colon cancer stage.
    J Womens Health (Larchmt), 14(6): 502-6. [Abstract] [Full-text]
  82. Malignant transformation of high-grade anal intraepithelial neoplasia.
    Br J Surg, 92(9): 1133-6. [Abstract] [Full-text]
  83. Treatment strategy for patients with colorectal cancer and synchronous irresectable liver metastases.
    Br J Surg, 92(9): 1155-60. [Abstract] [Full-text]
  84. Impact of anastomotic leakage on long-term survival of patients undergoing curative resection for colorectal cancer.
    Br J Surg, 92(9): 1150-4. [Abstract] [Full-text]
  85. Clinical significance of serum cytokine measurements in untreated colorectal cancer patients: soluble tumor necrosis factor receptor type I--an independent prognostic factor.
    Tumour Biol, 26(4): 186-94. [Abstract] [Full-text]
  86. Protective defunctioning stoma in low anterior resection for rectal carcinoma.
    Br J Surg, 92(9): 1137-42. [Abstract] [Full-text]
  87. Bladder and sexual function following resection for rectal cancer in a randomized clinical trial of laparoscopic versus open technique.
    Br J Surg, 92(9): 1124-32. [Abstract] [Full-text]
  88. Biopsy of resectable colorectal liver metastases causes tumour dissemination and adversely affects survival after liver resection.
    Br J Surg, 92(9): 1165-8. [Abstract] [Full-text]
  89. Prevalence of family history of colorectal cancer in the general population.
    Br J Surg, 92(9): 1161-4. [Abstract] [Full-text]
  90. Long-term use of aspirin and nonsteroidal anti-inflammatory drugs and risk of colorectal cancer.
    JAMA, 294(8): 914-23. [Abstract] [Full-text]
  91. A phase II trial of irinotecan, 5-fluorouracil and leucovorin combined with celecoxib and glutamine as first-line therapy for advanced colorectal cancer.
    Oncology, 69(1): 63-70. [Abstract] [Full-text]
  92. Continuous infusion of oxaliplatin plus chronomodulated capecitabine in 5-fluorouracil- and irinotecan-resistant advanced colorectal cancer patients.
    Oncology, 69(1): 27-34. [Abstract] [Full-text]
  93. Downregulation of EphA7 by hypermethylation in colorectal cancer.
    Oncogene, 24(36): 5637-47. [Abstract] [Full-text]
  94. Loss of heterozygosity on chromosome 10p14-p15 in colorectal carcinoma.
    Pathobiology, 72(4): 220-4. [Abstract] [Full-text]
  95. The spectrum of APC mutations in children with hepatoblastoma from familial adenomatous polyposis kindreds.
    J Pediatr, 147(2): 263-6. [Abstract] [Full-text]
  96. Mesorectal spread and micrometastasis of rectal cancer studied with large slice technique and tissue microarray.
    J Surg Oncol, 91(3): 167-72. [Abstract] [Full-text]
  97. Neutrophil-lymphocyte ratio as a prognostic factor in colorectal cancer.
    J Surg Oncol, 91(3): 181-4. [Abstract] [Full-text]
  98. Surgical wound healing complications in metastatic colorectal cancer patients treated with bevacizumab.
    J Surg Oncol, 91(3): 173-80. [Abstract] [Full-text]
  99. Colon cancer screening practices in New York City, 2003: results of a large random-digit dialed telephone survey.
    Cancer, 104(5): 1075-82. [Abstract] [Full-text]
  100. BRAF mutations in colorectal carcinoma suggest two entities of microsatellite-unstable tumors.
    Cancer, 104(5): 952-61. [Abstract] [Full-text]
  101. Cyclin D1 protein and CCND1 gene expression in colorectal cancer.
    Eur J Surg Oncol, 31(7): 721-6. [Abstract] [Full-text]
  102. Outcome after the introduction of a multimodality treatment program for locally advanced rectal cancer.
    Eur J Surg Oncol, 31(7): 727-34. [Abstract] [Full-text]
  103. New stool tests for colorectal cancer screening: a systematic review focusing on performance characteristics and practicalness.
    Int J Cancer, 117(2): 169-76. [Abstract] [Full-text]
  104. Expression of cytokeratins 7 and 20 in serrated adenoma and related diseases.
    Dig Dis Sci, 50(9): 1741-6. [Abstract] [Full-text]
  105. Postoperative 30-day mortality following surgical resection for colorectal cancer in veterans: changes in the right direction.
    Dig Dis Sci, 50(9): 1722-8. [Abstract] [Full-text]
  106. Effects of increasing doses of a bolus injection and an intravenous long-term therapy of taurolidine on subcutaneous (metastatic) tumor growth in rats.
    Clin Exp Metastasis, 22(1): 77-83. [Abstract] [Full-text]
  107. Lactate dehydrogenase 5 (LDH5) relates to up-regulated hypoxia inducible factor pathway and metastasis in colorectal cancer.
    Clin Exp Metastasis, 22(1): 25-30. [Abstract] [Full-text]
  108. Phenolic compounds from blueberries can inhibit colon cancer cell proliferation and induce apoptosis.
    J Agric Food Chem, 53(18): 7320-9. [Abstract] [Full-text]
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Colorectal Cancer Research Today Archive:

Volume 1 (2004)
  Issue 1 (August)
  Issue 2 (September)
  Issue 3 (October)
  Issue 4 (November)
  Issue 5 (December)

Volume 2 (2005)
  Issue 1 (January)
  Issue 2 (February)
  Issue 3 (March)
  Issue 4 (April)
  Issue 5 (May)
  Issue 6 (June)
  Issue 7 (July)
  Issue 8 (August)
  Issue 9 (September)
  Issue 10 (October)
  Issue 11 (November)
  Issue 12 (December)

Volume 3 (2006)
  Issue 1 (January)
  Issue 2 (February)
  Issue 3 (March)
  Issue 4 (April)
  Issue 5 (May)
  Issue 6 (June)
  Issue 7 (July)
  Issue 8 (August)
  Issue 9 (September)
  Issue 10 (October)
  Issue 11 (November)
  Issue 12 (December)

Volume 4 (2007)
  Issue 1 (January)
  Issue 2 (February)
  Issue 3 (March)
  Issue 4 (April)
  Issue 5 (May)
  Issue 6 (June)
  Issue 7 (July)
  Issue 8 (August)
  Issue 9 (September)
  Issue 10 (October)
  Issue 11 (November)
  Issue 12 (December)

Volume 5 (2008)
  Issue 1 (January)
  Issue 2 (February)
  Issue 3 (March)
  Issue 4 (April)
  Issue 5 (May)
  Issue 6 (June)
  Issue 7 (July)
  Issue 8 (August)
  Issue 9 (September)
  Issue 10 (October)
  Issue 11 (November)
  Issue 12 (December)

Volume 6 (2009)
  Issue 1 (January)
  Issue 2 (February)
  Issue 3 (March)
  Issue 4 (April)
  Issue 5 (May)
  Issue 6 (June)
  Issue 7 (July)
  Issue 8 (August)
  Issue 9 (September)
  Issue 10 (October)
  Issue 11 (November)
  Issue 12 (December)

Volume 7 (2010)
  Issue 1 (January)
  Issue 2 (February)
  Issue 3 (March)



Colorectal Cancer Books

The Intelligent Patient Guide to Colorectal Cancer: Information, risk, prevention, symptoms, signs, diagnosis, stage, surgery, radiation, chemotherapy, prognosis, treatment of/for colon rectal cancer.

The Intelligent Patient Guide to Colorectal Cancer: Information, risk, prevention, symptoms, signs, diagnosis, stage, surgery, radiation, chemotherapy, prognosis, treatment of/for colon rectal cancer.