Colorectal Cancer Research Today is a free monthly online journal that collates and summarizes the latest research about Colorectal Cancer, including details on symptoms, genetics, screening, treatment, information.

Volume 2 (2005), Issue 12 (December)

1. Long-term results in patients with T2-3 N0 distal rectal cancer undergoing radiotherapy before transanal endoscopic microsurgery.
   Br J Surg, 92(12): 1546-52. [Abstract] [Full-text]
2. Sentinel node detection after preoperative short-course radiotherapy in rectal carcinoma is not reliable.
   Br J Surg, 92(12): 1533-8. [Abstract] [Full-text]
3. Prostaglandin E2 promotes colon cancer cell growth through a Gs-axin-beta-catenin signaling axis.
   Science, 310(5753): 1504-10. [Abstract] [Full-text]
4. Phosphorylation of the homeotic tumor suppressor Cdx2 mediates its ubiquitin-dependent proteasome degradation.
   Oncogene, 24(54): 7955-63. [Abstract] [Full-text]
5. Combination B7-Fc fusion protein treatment and Treg cell depletion therapy.
   Clin Cancer Res, 11(23): 8492-502. [Abstract] [Full-text]
6. Site-specific drug delivery by photochemical internalization enhances the antitumor effect of bleomycin.
   Clin Cancer Res, 11(23): 8476-85. [Abstract] [Full-text]
7. Microsatellite instability and colorectal cancer prognosis.
   Clin Cancer Res, 11(23): 8332-40. [Abstract] [Full-text]
8. Differing DNA methylation patterns and gene mutation frequencies in colorectal carcinomas from Middle Eastern countries.
   Clin Cancer Res, 11(23): 8281-7. [Abstract] [Full-text]
9. Microarray analysis of the differential transformation mediated by Kirsten and Harvey Ras oncogenes in a human colorectal adenocarcinoma cell line.
   Int J Cancer, 118(3): 616-27. [Abstract] [Full-text]
10. Monitoring multiple angiogenesis-related molecules in the blood of cancer patients shows a correlation between VEGF-A and MMP-9 levels before treatment and divergent changes after surgical vs. conservative therapy.
    Int J Cancer, 118(3): 755-64. [Abstract] [Full-text]
11. Proliferation and Cdk4 expression in microsatellite unstable colon cancers with TGFBR2 mutations.
    Int J Cancer, 118(3): 600-8. [Abstract] [Full-text]
12. Occupational factors and risk of adult bone sarcomas: a multicentric case-control study in Europe.
    Int J Cancer, 118(3): 721-7. [Abstract] [Full-text]
13. Ursodeoxycholic acid inhibits interleukin 1 beta [corrected] and deoxycholic acid-induced activation of NF-kappaB and AP-1 in human colon cancer cells.
    Int J Cancer, 118(3): 532-9. [Abstract] [Full-text]
14. Conjugated linoleic acid inhibits peritoneal metastasis in human gastrointestinal cancer cells.
    Int J Cancer, 118(3): 571-6. [Abstract] [Full-text]
15. Identification of flat dysplastic aberrant crypt foci in the colon of azoxymethane-treated A/J mice.
    Int J Cancer, 118(3): 540-6. [Abstract] [Full-text]
16. Src family kinase members have a common response to histone deacetylase inhibitors in human colon cancer cells.
    Int J Cancer, 118(3): 547-54. [Abstract] [Full-text]
17. Microsatellite instability caused by hMLH1 promoter methylation increases with tumor progression in right-sided sporadic colorectal cancer.
    Oncology, 69(4): 354-62. [Abstract] [Full-text]
18. An examination of characteristics of lung and colon cancer patients participating in a web-based decision support program. Internet-based decision support programs.
    Oncology, 69(4): 311-6. [Abstract] [Full-text]
19. An alternating regimen of irinotecan/ 5-fluorouracil/folinic acid and oxaliplatin/ 5-fluorouracil/folinic acid in metastatic colorectal cancer: a Phase II trial.
    Oncology, 69(4): 283-9. [Abstract] [Full-text]
20. Adjuvant chemotherapy for stage III colon cancer: implications of race/ethnicity, age, and differentiation.
    JAMA, 294(21): 2703-11. [Abstract] [Full-text]
21. Expression of VDR and CYP24A1 mRNA in human tumors.
    Cancer Chemother Pharmacol, 57(2): 234-40. [Abstract] [Full-text]
22. Chemo-immunotherapy of metastatic colorectal carcinoma with gemcitabine plus FOLFOX 4 followed by subcutaneous granulocyte macrophage colony-stimulating factor and interleukin-2 induces strong immunologic and antitumor activity in metastatic colon cancer patients.
    J Clin Oncol, 23(35): 8950-8. [Abstract] [Full-text]
23. Low folate conditions may enhance the interaction of trifluorothymidine with antifolates in colon cancer cells.
    Cancer Chemother Pharmacol, 57(2): 171-9. [Abstract] [Full-text]
24. ILK over-expression in human colon cancer progression correlates with activation of beta-catenin, down-regulation of E-cadherin and activation of the Akt-FKHR pathway.
    J Pathol, 208(1): 91-9. [Abstract] [Full-text]
25. Monocyte chemoattractant protein 1 and macrophage cyclooxygenase 2 expression in colonic adenoma.
    Gut, 55(1): 54-61. [Abstract] [Full-text]
26. Effect of physical activity and body size on survival after diagnosis with colorectal cancer.
    Gut, 55(1): 62-7. [Abstract] [Full-text]
27. Whole body positron emission tomography/computed tomography (PET/CT) tumour staging with integrated PET/CT colonography: technical feasibility and first experiences in patients with colorectal cancer.
    Gut, 55(1): 68-73. [Abstract] [Full-text]
28. Combination therapy using the cyclooxygenase-2 inhibitor Parecoxib and radioimmunotherapy in nude mice with small peritoneal metastases of colonic origin.
    Cancer Immunol Immunother, 55(1): 47-55. [Abstract] [Full-text]
29. Dietary fiber intake and risk of colorectal cancer: a pooled analysis of prospective cohort studies.
    JAMA, 294(22): 2849-57. [Abstract] [Full-text]
30. The impact of fluor-18-deoxyglucose-positron emission tomography in the management of colorectal liver metastases.
    Cancer, 104(12): 2658-70. [Abstract] [Full-text]
31. Dual effect of Kras(D12) knockdown on tumorigenesis: increased immune-mediated tumor clearance and abrogation of tumor malignancy.
    Oncogene, 24(56): 8338-42. [Abstract] [Full-text]
32. Evaluation of ST13 gene expression in colorectal cancer patients.
    J Zhejiang Univ Sci B, 6(12): 1170-5. [Abstract] [Full-text]
33. Prognostic significance of bcl-2 and p53 expression in colorectal carcinoma.
    J Zhejiang Univ Sci B, 6(12): 1163-9. [Abstract] [Full-text]
34. Chemoprevention of colorectal cancer.
    Dis Colon Rectum, 49(1): 113-24; discussion 124-5. [Abstract] [Full-text]
35. Prediction of colorectal neoplasia by quantitative methylation analysis of estrogen receptor gene in nonneoplastic epithelium from patients with ulcerative colitis.
    Clin Cancer Res, 11(24): 8880-5. [Abstract] [Full-text]
36. Inclusion of vasculature-related variables in the Dukes staging system of colon cancer.
    Clin Cancer Res, 11(24): 8653-60. [Abstract] [Full-text]
37. Tumor beta-1,4-galactosyltransferase IV overexpression is closely associated with colorectal cancer metastasis and poor prognosis.
    Clin Cancer Res, 11(24): 8615-22. [Abstract] [Full-text]
38. The relationship between global methylation level, loss of heterozygosity, and microsatellite instability in sporadic colorectal cancer.
    Clin Cancer Res, 11(24): 8564-9. [Abstract] [Full-text]
39. The putative tumor suppressor Cdx2 is overexpressed by human colorectal adenocarcinomas.
    Clin Cancer Res, 11(24): 8549-56. [Abstract] [Full-text]
40. Combination analysis of activator protein-1 family members, Sp1 and an activator protein-2alpha-related factor binding to different regions of the urokinase receptor gene in resected colorectal cancers.
    Clin Cancer Res, 11(24): 8538-48. [Abstract] [Full-text]
41. Preoperative chemoradiation for rectal cancer causes prolonged pudendal nerve terminal motor latency.
    Dis Colon Rectum, 49(1): 12-9. [Abstract] [Full-text]
42. Surveillance colonoscopy in individuals at risk for hereditary nonpolyposis colorectal cancer: an evidence-based review.
    Dis Colon Rectum, 49(1): 80-93; discussion 94-5. [Abstract] [Full-text]
43. Comparison of characteristics and survival of colorectal cancer between Japanese-Americans in Hawaii and native Japanese in Japan.
    Dis Colon Rectum, 49(1): 50-7. [Abstract] [Full-text]
44. Outcomes for abdominoperineal resections are not worse than those of anterior resections.
    Dis Colon Rectum, 49(1): 41-9. [Abstract] [Full-text]
45. Expectant management of anal squamous dysplasia in patients with HIV.
    Dis Colon Rectum, 49(1): 36-40. [Abstract] [Full-text]
46. High resolution anoscopy and targeted treatment of high-grade squamous intraepithelial lesions.
    Dis Colon Rectum, 49(1): 126. [Abstract] [Full-text]
47. Repeat hepatectomy for recurrent colorectal liver metastases.
    J Surg Oncol, 93(1): 1-7. [Abstract] [Full-text]
48. Isolated tumor cells in lymph nodes are not a prognostic marker for patients with stage I and stage II colorectal cancer.
    J Surg Oncol, 93(1): 13-8; discussion 18-9. [Abstract] [Full-text]
49. The trans-metastasis hepatectomy (through metastases previously ablated with radiofrequency): results of a 13-case study of colorectal cancer.
    J Surg Oncol, 93(1): 8-12. [Abstract] [Full-text]
50. Upregulation of thymidine phosphorylase in rectal cancer tissues by mitomycin C.
    J Surg Oncol, 93(1): 47-55. [Abstract] [Full-text]
51. Altered growth patterns of colorectal liver metastases after thermal ablation.
    Surgery, 139(1): 73-81. [Abstract] [Full-text]
52. Overexpression of ADAM9 enhances growth factor-mediated recycling of E-cadherin in human colon cancer cell line HT29 cells.
    Exp Cell Res, 312(3): 331-9. [Abstract] [Full-text]
53. Evidence for serpinB2-independent protection from TNF-alpha-induced apoptosis.
    Exp Cell Res, 312(3): 350-61. [Abstract] [Full-text]
54. Effector memory T cells, early metastasis, and survival in colorectal cancer.
    N Engl J Med, 353(25): 2654-66. [Abstract] [Full-text]
55. A pilot study on the safety of combining chrysin, a non-absorbable inducer of UGT1A1, and irinotecan (CPT-11) to treat metastatic colorectal cancer.
    Cancer Chemother Pharmacol, 57(3): 309-16. [Abstract] [Full-text]
56. Molecular profiling of ulcerative colitis-associated neoplastic progression.
    Exp Mol Pathol, 80(1): 1-10. [Abstract] [Full-text]
57. Tetracycline analogues (doxycycline and COL-3) induce caspase-dependent and -independent apoptosis in human colon cancer cells.
    Int J Cancer, 118(5): 1309-15. [Abstract] [Full-text]
58. Radiological findings do not support lateral residual tumour as a major cause of local recurrence of rectal cancer.
    Br J Surg, 93(1): 113-9. [Abstract] [Full-text]
59. Local recurrence after curative resection for rectal cancer is associated with anterior position of the tumour.
    Br J Surg, 93(1): 105-12. [Abstract] [Full-text]

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