Colorectal Cancer Research Today is a free monthly online journal that collates and summarizes the latest research about Colorectal Cancer, including details on symptoms, genetics, screening, treatment, information.

Volume 1 (2004), Issue 5 (December)

1. Netrin-1 and its receptors in tumorigenesis.
   Nat Rev Cancer, 4(12): 978-87. [Abstract] [Full-text]
2. Clinical relevance of thymidylate synthase expression in the signet ring cell histotype component of colorectal carcinoma.
   Eur J Cancer, 40(18): 2845-50. [Abstract] [Full-text]
3. Six novel heterozygous MLH1, MSH2, and MSH6 and one homozygous MLH1 germline mutations in hereditary nonpolyposis colorectal cancer.
   Cancer Genet Cytogenet, 155(2): 149-51. [Abstract] [Full-text]
4. Genome signatures of colon carcinoma cell lines.
   Cancer Genet Cytogenet, 155(2): 119-31. [Abstract] [Full-text]
5. SMAC/Diablo-dependent apoptosis induced by nonsteroidal antiinflammatory drugs (NSAIDs) in colon cancer cells.
   Proc Natl Acad Sci U S A, 101(48): 16897-902. [Abstract] [Full-text]
6. n-3 PUFAs reduce VEGF expression in human colon cancer cells modulating the COX-2/PGE2 induced ERK-1 and -2 and HIF-1alpha induction pathway.
   Carcinogenesis, 25(12): 2303-10. [Abstract] [Full-text]
7. Genetic polymorphisms in UDP-glucuronosyltransferases and glutathione S-transferases and colorectal cancer risk.
   Carcinogenesis, 25(12): 2407-15. [Abstract] [Full-text]
8. Epicatechin gallate-induced expression of NAG-1 is associated with growth inhibition and apoptosis in colon cancer cells.
   Carcinogenesis, 25(12): 2425-32. [Abstract] [Full-text]
9. Arachidonate lipoxygenase (ALOX) and cyclooxygenase (COX) polymorphisms and colon cancer risk.
   Carcinogenesis, 25(12): 2467-72. [Abstract] [Full-text]
10. Effects of a combination of docosahexaenoic acid and 1,4-phenylene bis(methylene) selenocyanate on cyclooxygenase 2, inducible nitric oxide synthase and beta-catenin pathways in colon cancer cells.
    Carcinogenesis, 25(12): 2443-9. [Abstract] [Full-text]
11. The histone deacetylase inhibitor suberoylanilide hydroxamic acid induces apoptosis via induction of 15-lipoxygenase-1 in colorectal cancer cells.
    Cancer Res, 64(23): 8778-81. [Abstract] [Full-text]
12. Self-care for stoma surgery: mastering independent stoma self-care skills in an elderly woman.
    Nurs Sci Q, 18(1): 66-9. [Abstract] [Full-text]
13. Laparoscopy in the management of colorectal cancer metastatic to the liver.
    ANZ J Surg, 74(12): 1056-9. [Abstract] [Full-text]
14. Narrow-band imaging in the diagnosis of colorectal mucosal lesions: a pilot study.
    Endoscopy, 36(12): 1094-8. [Abstract] [Full-text]
15. Chromoendoscopy using indigo carmine dye spraying with magnifying observation is the most reliable method for differential diagnosis between non-neoplastic and neoplastic colorectal lesions: a prospective study.
    Endoscopy, 36(12): 1089-93. [Abstract] [Full-text]
16. Comparison of capsule endoscopy and magnetic resonance imaging for the detection of polyps of the small intestine in patients with familial adenomatous polyposis or with Peutz-Jeghers' syndrome.
    Endoscopy, 36(12): 1054-9. [Abstract] [Full-text]
17. Associations between BMI, energy intake, energy expenditure, VDR genotype and colon and rectal cancers (United States).
    Cancer Causes Control, 15(9): 863-72. [Abstract] [Full-text]
18. Dietary patterns and risk of colon cancer and adenoma in a cohort of men (United States).
    Cancer Causes Control, 15(9): 853-62. [Abstract] [Full-text]
19. Detecting changes in the relative expression of KRAS2 splice variants using polymerase colonies.
    Biotechnol Prog, 20(6): 1836-9. [Abstract] [Full-text]
20. Adjuvant hepatic arterial infusion after curative resection of colorectal liver metastases using removable intra-arterial catheters with shape-memory alloy.
    J Surg Oncol, 88(4): 248-55. [Abstract] [Full-text]
21. Two colons-two cancers: paradigm shift and clinical implications.
    J Surg Oncol, 88(4): 261-6. [Abstract] [Full-text]
22. Haemostatic alterations in colorectal cancer: perspectives for future treatment.
    J Surg Oncol, 88(4): 269-75. [Abstract] [Full-text]
23. Intraoperative adverse events and outcome after anterior resection of the rectum.
    Br J Surg, 91(12): 1608-12. [Abstract] [Full-text]
24. PTH-related protein enhances LoVo colon cancer cell proliferation, adhesion, and integrin expression.
    Regul Pept, 125(1): 17-27. [Abstract] [Full-text]
25. Bile acid induced gene expression in LT97 colonic adenoma cells.
    Food Chem Toxicol, 43(1): 87-93. [Abstract] [Full-text]
26. The use of transrectal ultrasound to biopsy pelvic masses in women.
    Gynecol Oncol, 95(3): 552-6. [Abstract] [Full-text]
27. Adjuvant interleukin-12 gene therapy for the management of colorectal liver metastases.
    Cancer Gene Ther, 11(12): 782-9. [Abstract] [Full-text]
28. A normal organ antigen and its corresponding antibodies in pathological human sera.
    Int Arch Allergy Immunol, 135(3): 243-6. [Abstract] [Full-text]
29. Involvement of the chaperone tapasin in HLA-B44 allelic losses in colorectal tumors.
    Int J Cancer, 113(4): 611-8. [Abstract] [Full-text]
30. Transcriptome analysis of a human colorectal cancer cell line shows molecular targets of insulin-like growth factor-binding protein-4 overexpression.
    Int J Cancer, 113(4): 588-99. [Abstract] [Full-text]
31. Herpes simplex virus thymidine kinase gene transduction enhances tumor growth rate and cyclooxygenase-2 expression in murine colon cancer cells.
    Cancer Gene Ther, 11(12): 830-40. [Abstract] [Full-text]
32. Interplay of insulin-like growth factor-II, insulin-like growth factor-I, insulin-like growth factor-I receptor, COX-2, and matrix metalloproteinase-7, play key roles in the early stage of colorectal carcinogenesis.
    Clin Cancer Res, 10(23): 7950-7. [Abstract] [Full-text]
33. Targeting of HER2 antigen for the treatment of disseminated peritoneal disease.
    Clin Cancer Res, 10(23): 7834-41. [Abstract] [Full-text]
34. Evaluation of Charlson-Age Comorbidity Index as predictor of morbidity and mortality in patients with colorectal carcinoma.
    J Gastrointest Surg, 8(8): 1061-7. [Abstract] [Full-text]
35. Integrins can directly mediate metastatic tumor cell adhesion within the liver sinusoids.
    J Gastrointest Surg, 8(8): 1049-59; discussion 1060. [Abstract] [Full-text]
36. Lymph node metastasis in T1 adenocarcinoma of the colon and rectum.
    J Gastrointest Surg, 8(8): 1032-9; discussion 1039-40. [Abstract] [Full-text]
37. Molecular biology of squamous cell carcinoma of the anus: a comparison of HIV-positive and HIV-negative patients.
    J Gastrointest Surg, 8(8): 1024-30; discussion 1031. [Abstract] [Full-text]
38. Differentiation of human colon adenocarcinoma cells alters the expression and intracellular localization of annexins A1, A2, and A5.
    J Cell Biochem, 94(1): 178-93. [Abstract] [Full-text]
39. Predictors of adherence and contamination in a randomized trial of exercise in colorectal cancer survivors.
    Psychooncology, 13(12): 857-66. [Abstract] [Full-text]
40. Low level microsatellite instability may be associated with reduced cancer specific survival in sporadic stage C colorectal carcinoma.
    Gut, 54(1): 103-8. [Abstract] [Full-text]
41. Cost effectiveness of a new strategy to identify HNPCC patients.
    Gut, 54(1): 97-102. [Abstract] [Full-text]
42. The role of gelatinases in colorectal cancer progression and metastasis.
    Biochim Biophys Acta, 1705(2): 69-89. [Abstract] [Full-text]
43. Green-coloured results on guaiac-based faecal occult blood testing should be considered positive.
    Ann Clin Biochem, 41: 488-90. [Abstract] [Full-text]
44. Impact of functional support on health-related quality of life in patients with colorectal cancer.
    Cancer, 101(12): 2737-43. [Abstract] [Full-text]
45. Colorectal carcinoma mortality among Appalachian men and women, 1969-1999.
    Cancer, 101(12): 2851-8. [Abstract] [Full-text]
46. Isolation and characterization of a novel gene CLUAP1 whose expression is frequently upregulated in colon cancer.
    Oncogene, 23(57): 9289-94. [Abstract] [Full-text]
47. Tobacco use and increased colorectal cancer risk in patients with hereditary nonpolyposis colorectal cancer (Lynch syndrome).
    Arch Intern Med, 164(22): 2429-31. [Abstract] [Full-text]
48. Expression of the high-affinity selectin glycan ligand C2-O-sLeX by colon carcinoma cells.
    Cancer Lett, 217(1): 105-13. [Abstract] [Full-text]
49. Mortalin is over-expressed by colorectal adenocarcinomas and correlates with poor survival.
    J Pathol, 205(1): 74-81. [Abstract] [Full-text]
50. Genes upregulated in a metastasizing human colon carcinoma cell line.
    Int J Cancer, 113(5): 699-705. [Abstract] [Full-text]
51. Folate intake and colorectal cancer risk: a meta-analytical approach.
    Int J Cancer, 113(5): 825-8. [Abstract] [Full-text]
52. Red meat consumption and risk of cancers of the proximal colon, distal colon and rectum: the Swedish Mammography Cohort.
    Int J Cancer, 113(5): 829-34. [Abstract] [Full-text]
53. Dosing and scheduling influence the antitumor efficacy of a phosphinic peptide inhibitor of matrix metalloproteinases.
    Int J Cancer, 113(5): 775-81. [Abstract] [Full-text]
54. Low doses of beta-carotene and lutein inhibit AOM-induced rat colonic ACF formation but high doses augment ACF incidence.
    Int J Cancer, 113(5): 798-802. [Abstract] [Full-text]
55. Radio-frequency ablation of colorectal liver metastases in 167 patients.
    Eur Radiol, 14(12): 2261-7. [Abstract] [Full-text]
56. Impact of EGFR expression on colorectal cancer patient prognosis and survival.
    Ann Oncol, 16(1): 102-8. [Abstract] [Full-text]
57. 15-Hydroxyprostaglandin dehydrogenase, a COX-2 oncogene antagonist, is a TGF-beta-induced suppressor of human gastrointestinal cancers.
    Proc Natl Acad Sci U S A, 101(50): 17468-73. [Abstract] [Full-text]
58. Phase- and size-adjusted CT cut-off for differentiating neoplastic lesions from normal colon in contrast-enhanced CT colonography.
    Eur Radiol, 14(12): 2228-35. [Abstract] [Full-text]
59. The human tumor suppressor CEACAM1 modulates apoptosis and is implicated in early colorectal tumorigenesis.
    Oncogene, 23(58): 9306-13. [Abstract] [Full-text]
60. Family physicians' perspectives on practice guidelines related to cancer control.
    BMC Fam Pract, 5: 25. [Abstract] [Full-text]
61. Prognostic significance of Subjective Global Assessment (SGA) in advanced colorectal cancer.
    Eur J Clin Nutr, 59(1): 35-40. [Abstract] [Full-text]
62. Elimination of hepatic metastases of colon cancer cells via p53-independent cross-talk between irinotecan and Apo2 ligand/TRAIL.
    Cancer Res, 64(24): 9105-14. [Abstract] [Full-text]
63. Tetrandrine induces early G1 arrest in human colon carcinoma cells by down-regulating the activity and inducing the degradation of G1-S-specific cyclin-dependent kinases and by inducing p53 and p21Cip1.
    Cancer Res, 64(24): 9086-92. [Abstract] [Full-text]
64. Conditional ROCK activation in vivo induces tumor cell dissemination and angiogenesis.
    Cancer Res, 64(24): 8994-9001. [Abstract] [Full-text]
65. Clear cell adenocarcinoma of the rectum.
    Med Princ Pract, 14(1): 58-60. [Abstract] [Full-text]
66. Natural killer cells infiltrating colorectal cancer and MHC class I expression.
    Mol Immunol, 42(4): 541-6. [Abstract] [Full-text]
67. 17beta-Estradiol rapidly stimulates c-fos expression via the MAPK pathway in T84 cells.
    Mol Cell Endocrinol, 229(1): 39-47. [Abstract] [Full-text]
68. Older patients' experiences of treatment for colorectal cancer: an analysis of functional status and service use.
    Eur J Cancer Care (Engl), 13(5): 483-93. [Abstract] [Full-text]
69. Hospital volume and outcome of rectal cancer surgery in Denmark 1994-99.
    Colorectal Dis, 7(1): 90-5. [Abstract] [Full-text]
70. Endoscopic laser ablation of advanced rectal carcinoma--a DGH experience.
    Colorectal Dis, 7(1): 58-60. [Abstract] [Full-text]
71. Anastomotic leakage following routine mesorectal excision for rectal cancer in a national cohort of patients.
    Colorectal Dis, 7(1): 51-7. [Abstract] [Full-text]
72. Endoscopic transanal resection of rectal tumours using a urological resectoscope--still has a role in selected patients.
    Colorectal Dis, 7(1): 47-50. [Abstract] [Full-text]
73. Multicentre prospective audit of surgical outcomes and acute complications following short course pre-operative radiotherapy for resectable rectal cancer.
    Colorectal Dis, 7(1): 43-6. [Abstract] [Full-text]
74. Evaluation of a pre-operative staging protocol in the management of colorectal carcinoma.
    Colorectal Dis, 7(1): 35-42. [Abstract] [Full-text]
75. Recent randomised trials in colorectal disease.
    Colorectal Dis, 7(1): 8-17. [Abstract] [Full-text]
76. Water induces autocrine stimulation of tumor cell killing through ATP release and P2 receptor binding.
    Cell Death Differ, 11: S172-80. [Abstract] [Full-text]
77. Refining the Amsterdam Criteria and Bethesda Guidelines: testing algorithms for the prediction of mismatch repair mutation status in the familial cancer clinic.
    J Clin Oncol, 22(24): 4934-43. [Abstract] [Full-text]
78. Diagnostic laparoscopy prior to planned hepatic resection for colorectal metastases.
    Arch Surg, 139(12): 1326-30. [Abstract] [Full-text]
79. Risk of colorectal adenomas in a multiethnic Asian patient population: race does not matter.
    J Gastroenterol Hepatol, 20(1): 51-5. [Abstract] [Full-text]
80. Ostomy patients' perceptions of quality of care.
    J Adv Nurs, 49(1): 51-8. [Abstract] [Full-text]
81. Palliation of malignant rectal obstruction with self-expanding metal stents.
    Surgery, 137(1): 42-7. [Abstract] [Full-text]
82. Surgical treatment for colorectal liver metastases involving the paracaval portion of the caudate lobe.
    Surgery, 137(1): 26-32. [Abstract] [Full-text]
83. Long-term outcomes of a neo-anus with a pudendal nerve anastomosis contemporaneously reconstructed with an abdominoperineal excision of the rectum.
    Surgery, 137(1): 8-15. [Abstract] [Full-text]
84. Genetic characterization of Chinese hereditary non-polyposis colorectal cancer by DHPLC and multiplex PCR.
    Jpn J Clin Oncol, 34(11): 660-6. [Abstract] [Full-text]
85. Polymorphism of the p73 gene in relation to colorectal cancer risk and survival.
    Carcinogenesis, 26(1): 103-7. [Abstract] [Full-text]
86. Induction of macroautophagy in human colon cancer cells by soybean B-group triterpenoid saponins.
    Carcinogenesis, 26(1): 159-67. [Abstract] [Full-text]
87. Colonic adenocarcinomas rapidly induced by the combined treatment with 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and dextran sodium sulfate in male ICR mice possess beta-catenin gene mutations and increases immunoreactivity for beta-catenin, cyclooxygenase-2 and inducible nitric oxide synthase.
    Carcinogenesis, 26(1): 229-38. [Abstract] [Full-text]
88. Molecular analysis of APC promoter methylation and protein expression in colorectal cancer metastasis.
    Carcinogenesis, 26(1): 37-43. [Abstract] [Full-text]
89. Rectal adenocarcinoma metastatic to the thyroid gland.
    Int J Clin Oncol, 9(6): 515-9. [Abstract] [Full-text]
90. Fecal DNA versus fecal occult blood for colorectal-cancer screening in an average-risk population.
    N Engl J Med, 351(26): 2704-14. [Abstract] [Full-text]
91. The management of rectal cancer in the elderly.
    Surg Oncol, 13(4): 223-34. [Abstract] [Full-text]
92. Age-related variations in progression of cancer at diagnosis and completeness of cancer registry data.
    Surg Oncol, 13(4): 175-9. [Abstract] [Full-text]
93. The nonsteroidal anti-inflammatory drug, nabumetone, differentially inhibits beta-catenin signaling in the MIN mouse and azoxymethane-treated rat models of colon carcinogenesis.
    Cancer Lett, 217(2): 161-9. [Abstract] [Full-text]
94. Down-regulation of DNA polymerases kappa, eta, iota, and zeta in human lung, stomach, and colorectal cancers.
    Cancer Lett, 217(2): 139-47. [Abstract] [Full-text]
95. Rectal cancer: MR imaging in local staging--is gadolinium-based contrast material helpful?
    Radiology, 234(1): 179-88. [Abstract] [Full-text]
96. Minimally invasive surgery for rectal cancer.
    Surg Clin North Am, 85(1): 61-73, ix. [Abstract] [Full-text]
97. Laparoscopic surgery for colon cancer.
    Surg Clin North Am, 85(1): 49-60, viii. [Abstract] [Full-text]
98. Morbidity of adjuvant hepatic arterial infusion pump chemotherapy in the management of colorectal cancer metastatic to the liver.
    Am J Surg, 188(6): 714-21. [Abstract] [Full-text]
99. Use of laser for rectal lesions in poor-risk patients.
    Am J Surg, 188(6): 708-13. [Abstract] [Full-text]
100. A novel high-specificity approach for colorectal neoplasia: Detection of K-ras2 oncogene mutation in normal mucosa.
     Int J Cancer, 113(6): 1015-21. [Abstract] [Full-text]
101. Preoperative iron supplementation and intraoperative transfusion during colorectal cancer surgery.
     Surg Today, 35(1): 36-40. [Abstract] [Full-text]
102. Long-term survival after salvage surgery for colorectal lung metastases.
     Ann Thorac Surg, 79(1): 325-6. [Abstract] [Full-text]
103. Histopathologic prognostic factors in resected colorectal lung metastases.
     Ann Thorac Surg, 79(1): 278-82; discussion 283. [Abstract] [Full-text]
104. A novel beta1,3-N-acetylglucosaminyltransferase (beta3Gn-T8), which synthesizes poly-N-acetyllactosamine, is dramatically upregulated in colon cancer.
     FEBS Lett, 579(1): 71-8. [Abstract] [Full-text]
105. Mouse homologue of a novel human oncofetal antigen, glypican-3, evokes T-cell-mediated tumor rejection without autoimmune reactions in mice.
     Clin Cancer Res, 10(24): 8630-40. [Abstract] [Full-text]
106. Ring finger protein 43 as a new target for cancer immunotherapy.
     Clin Cancer Res, 10(24): 8577-86. [Abstract] [Full-text]
107. Prognostic impact of hypoxia-inducible factors 1alpha and 2alpha in colorectal cancer patients: correlation with tumor angiogenesis and cyclooxygenase-2 expression.
     Clin Cancer Res, 10(24): 8554-60. [Abstract] [Full-text]
108. Cyclooxygenase-2 expression: a significant prognostic indicator for patients with colorectal cancer.
     Clin Cancer Res, 10(24): 8465-71. [Abstract] [Full-text]
109. Low levels of insulin-like growth factor type 1 receptor expression at cancer cell membrane predict liver metastasis in Dukes' C human colorectal cancers.
     Clin Cancer Res, 10(24): 8434-41. [Abstract] [Full-text]
110. Artificial neural networks analysis of surface-enhanced laser desorption/ionization mass spectra of serum protein pattern distinguishes colorectal cancer from healthy population.
     Clin Cancer Res, 10(24): 8380-5. [Abstract] [Full-text]
111. Genetic polymorphisms of human flavin monooxygenase 3 in sulindac-mediated primary chemoprevention of familial adenomatous polyposis.
     Clin Cancer Res, 10(24): 8357-62. [Abstract] [Full-text]
112. Tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis is inhibited by Bcl-2 but restored by the small molecule Bcl-2 inhibitor, HA 14-1, in human colon cancer cells.
     Clin Cancer Res, 10(24): 8284-92. [Abstract] [Full-text]
113. Coexpression of matrix metalloproteinase-7 (MMP-7) and epidermal growth factor (EGF) receptor in colorectal cancer: an EGF receptor tyrosine kinase inhibitor is effective against MMP-7-expressing cancer cells.
     Clin Cancer Res, 10(24): 8243-9. [Abstract] [Full-text]
114. Matrix metalloproteinase/tissue inhibitors of matrix metalloproteinase phenotype identifies poor prognosis colorectal cancers.
     Clin Cancer Res, 10(24): 8229-34. [Abstract] [Full-text]
115. Intraductal papillary mucinous neoplasm of the pancreas in a patient with attenuated familial adenomatous polyposis.
     J Clin Pathol, 58(1): 97-101. [Abstract] [Full-text]
116. Desmoplasia measured by computer assisted image analysis: an independent prognostic marker in colorectal carcinoma.
     J Clin Pathol, 58(1): 32-8. [Abstract] [Full-text]
117. Long-term results of preoperative chemoradiation for distal rectal cancer correlation between final stage and survival.
     J Gastrointest Surg, 9(1): 90-9; discussion 99-101. [Abstract] [Full-text]
118. Differential DNA hypermethylation and hypomethylation signatures in colorectal cancer.
     Hum Mol Genet, 14(2): 319-26. [Abstract] [Full-text]
119. Low levels of microsatellite instability characterize MLH1 and MSH2 HNPCC carriers before tumor diagnosis.
     Hum Mol Genet, 14(2): 235-9. [Abstract] [Full-text]
120. Strong expression of methylthioadenosine phosphorylase (MTAP) in human colon carcinoma cells is regulated by TCF1/[beta]-catenin.
     Lab Invest, 85(1): 124-36. [Abstract] [Full-text]
121. Platelet activation in patients with colorectal cancer.
     Prostaglandins Leukot Essent Fatty Acids, 72(2): 79-83. [Abstract] [Full-text]
122. Prostaglandin E2 regulates the complement inhibitor CD55/decay-accelerating factor in colorectal cancer.
     J Biol Chem, 280(1): 476-83. [Abstract] [Full-text]

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